Results 31 to 40 of about 13,805 (198)
Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy
Pharmaceutics, 2023 The precise delivery of cytotoxic radiation to cancer cells through the combination of a specific targeting vector with a radionuclide for targeted radionuclide therapy (TRT) has proven valuable for cancer care.
Cyprine Neba Funeh +8 more
doaj +1 more source
PEPTIDE BASED TARGETED RADIONUCLIDE THERAPIES; SCIENCE BEHIND THE SUCCESS.
Journal of Cancer and Allied Specialties, 2016 The radionuclide therapies for solid and liquid malignancies are emerging field nowadays. The targeted radionuclide therapies have been in use since 1945.
Mohammed H Al Rowaily +4 more
doaj +1 more source
A High Separation Factor for 165Er from Ho for Targeted Radionuclide Therapy
Molecules, 2021 Background: Radionuclides emitting Auger electrons (AEs) with low (0.02–50 keV) energy, short (0.0007–40 µm) range, and high (1–10 keV/µm) linear energy transfer may have an important role in the targeted radionuclide therapy of metastatic and ...
Isidro Da Silva +7 more
doaj +1 more source
Radiopharmaceuticals: From Molecular Imaging to Targeted Radionuclide Therapy
CHIMIA, 2004 The research and development of smart radiodrugs is the goal of the Center of Radiopharmaceutical Science of ETH, PSI, and USZ. Positron Emission Tomography (PET) allows the non-invasive visualization of biochemical processes within the body ...
P. August Schubiger +8 more
doaj +1 more source
Radiological Technology for Targeted Radionuclide Therapy
Japanese Journal of Radiological Technology, 2020 Targeted radioisotope therapy (TRT) is a radiotherapy using radioisotope or drug incorporating it and has been used as a treatment for selectively irradiating cancer cells. In recent years, interest in TRT has increased due to improvements in radionuclide production technology, development of new drugs and imaging modalities, and improvements in ...
Kohei, Hanaoka +7 more
openaire +3 more sources
Alpha‐emitters and targeted alpha therapy in cancer treatment
iRADIOLOGY, 2023 Alpha emitters are radionuclides with good pharmacological characteristics for the treatment of cancer because they decay by emitting high linear energy transfer particles.
Jiajia Zhang +5 more
doaj +1 more source
A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice
Molecules, 2018 We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom.
Steve Swenson +5 more
doaj +1 more source
Targeted alpha-particle therapy in neuroendocrine neoplasms: A systematic review
World Journal of Nuclear Medicine, 2021 Neuroendocrine neoplasms (NENs) are a very diverse group of tumors with a worldwide rise in incidence. Systemic therapy remains the mainstay treatment for unresectable and/or metastatic NENs.
Thuan Koh +3 more
doaj +1 more source
Targeted Palliative Radionuclide Therapy for Metastatic Bone Pain [PDF]
Journal of Clinical Medicine, 2020 Bone metastasis develops in multiple malignancies with a wide range of incidence. The presence of multiple bone metastases, leading to a multitude of complications and poorer prognosis. The corresponding refractory bone pain is still a challenging issue managed through multidisciplinary approaches to enhance the quality of life.
Reyhaneh Manafi-Farid +8 more
openaire +3 more sources
Targeting Melanin in Melanoma with Radionuclide Therapy
International Journal of Molecular Sciences, 2022 Nearly 100,000 individuals are expected to be diagnosed with melanoma in the United States in 2022. Treatment options for late-stage metastatic disease up until the 2010s were few and offered only slight improvement to the overall survival. The introduction of B-RAF inhibitors and anti-CTLA4 and anti-PD-1/PD-L1 immunotherapies into standard of care ...
Kevin J. H. Allen +3 more
openaire +2 more sources