Results 221 to 230 of about 1,721,954 (363)

Lung Cancer: Targeted Therapy in 2025. [PDF]

Curr Oncol
Bouchard N, Daaboul N.
europepmc   +1 more source

Receptors of the enteric nervous system: potential targets for drug therapy [PDF]

, 2000
Jan Tack
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Targeted Therapies; Who Detects the Target?

Analytical Cellular Pathology, 2005
Gerrit A. Meijer, J. J. Oudejans
openaire   +4 more sources

Ovarian cancer targeted therapy: current landscape and future challenges. [PDF]

Front Oncol
Wang G, Yang H, Wang Y, Qin J.
europepmc   +1 more source

Construction of Gene Therapy Vectors Targeting Adrenocortical Cells: Enhancement of Activity and Specificity with Agents Modulating the Cyclic Adenosine 3′,5′-Monophosphate Pathway [PDF]

, 2000
Yutaka Chuman, Zhirong Zhan, Tito Fojo
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Addressing Challenges in Targeted Therapy for Metastatic Colorectal Cancer. [PDF]

Cancers (Basel)
El Hage M, Su Z, Linnebacher M.
europepmc   +1 more source

Which Targets Are Relevant for Therapy of Acute Ischemic Stroke? [PDF]

, 2000
Marc Fisher, Jean‐Claude Baron
openalex   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source