Results 251 to 260 of about 1,817,538 (306)

Targeting Targeted Therapies

Immunotherapy, 2010
745 ISSN 1750-743X Immunotherapy (2010) 2(6), 745–748 10.2217/IMT.10.66 © 2010 Future Medicine Ltd “Although it would be naive to conclude that biomarker programs are cheap and straightforward, it is likely to be a price worth paying in order to maximize the chance of success in the tortuous process of cancer drug development, and, ultimately, to ...
William, Shingler, Richard, Harrop
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Targeted photodynamic therapy

Lasers in Surgery and Medicine, 2006
AbstractBackground and ObjectivesPhotodynamic therapy (PDT) is an emerging modality for the treatment of various neoplastic and non‐neoplastic pathologies.Study Design/Materials and MethodsPDT usually occurs when reactive oxygen species (ROS) generated from light‐activated chemicals (photosensitizer, PS) destroy the target.
Nicolas, Solban   +2 more
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Targeted gene therapy

British Medical Bulletin, 1995
Melanin biosynthesis is limited to melanocytes partly as a consequence of transcriptional regulation of the enzymes involved in this pathway. Promoter sequences of these enzyme genes may be utilised to drive expression of complementary DNA coding for therapeutic genes so as to provide transcriptional targeting. We have used the 5'-flanking sequences of
I R, Hart, R G, Vile
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EGFR-targeted therapy

Experimental Cell Research, 2011
Anti-Epidermal Growth Factor Receptor (EGFR) therapies have been recently developed for the treatment of multiple cancer types. At the time when they were introduced in clinical practice, there was little knowledge of the molecular bases of tumor sensitivity and resistance to these novel targeted compounds.
Vecchione L   +4 more
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Targeting Targeted Therapy

New England Journal of Medicine, 2004
The emergence of effective cancer chemotherapy is one of the major medical advances of the second half of the 20th century. In certain neoplasms — such as gestational choriocarcinoma, childhood acute lymphoblastic leukemia, and subgroups of Hodgkin's disease and non-Hodgkin's lymphoma — chemotherapy is often curative, and the promise of long-term ...
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