Results 281 to 290 of about 10,512,166 (412)

Influenza Fusogenic Peptide in DNA Complex Enhances Asialoglycoprotein Receptor-Mediated Gene Transfer to Hepatoma Cells: A Strategy for Liver-Targeting Gene Therapy.

, 1997
Masato Miyauchi, Sanae Hisayasu, Takashi Shimada   +2 more
openalex   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Colorectal Cancer: Pathogenesis and Targeted Therapy. [PDF]

MedComm (2020)
Li J, Pan J, Wang L, Ji G, Dang Y.
europepmc   +1 more source

Harnessing lentiviral vectors for in vivo gene therapy of liver metastases

Clinical and Translational Medicine
Giovanna Giacca, Luigi Naldini, Mario Leonardo Squadrito   +2 more
doaj   +1 more source

Current and future antifungal therapy: new targets for antifungal therapy

, 2000
Vincent T. Andriole
openalex   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Targeted therapy: What are the targets?

The Indian Journal of Neurotrauma, 2005
openaire   +3 more sources

A transgenic mouse line that develops early‐onset invasive gastric carcinoma provides a model for carcinoembryonic antigen‐targeted tumor therapy [PDF]

, 2000
John A. Thompson, Thomas Epting, Georg Schwarzkopf, Axel Singhofen, Anne‐Marie Eades‐Perner, Herman van der Putten, Wolfgang Zimmermann   +6 more
openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Targeted therapy for idiopathic pulmonary fibrosis: a bibliometric analysis of 2004-2024. [PDF]

Front Med (Lausanne)
Zhang X, Yuan Z, Shi X, Yang J.
europepmc   +1 more source