Results 311 to 320 of about 10,512,166 (412)

The key role of the ferroptosis mechanism in neurological diseases and prospects for targeted therapy. [PDF]

Front Neurosci
Xie C, Wu N, Guo J, Ma L, Zhang C.
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

HPV-driven cancers: a looming threat and the potential of CRISPR/Cas9 for targeted therapy. [PDF]

Virol J
Kermanshahi AZ, Ebrahimi F, Taherpoor A, Eslami N, Baghi HB.   +4 more
europepmc   +1 more source

Targeted therapy in gastric cancer [PDF]

, 2016

core   +1 more source

Radiopharmaceuticals for Targeted Tumor Diagnosis and Therapy

, 2000
Robert Waibel, Ilse Novak‐Hofer, Roger Schibli, Peter Bläuenstein, Elisa García‐Garayoa, R. Schwarzbach, Kurt Zimmermann, Raimo Pellikka, Olga Gasser, Alain Blanc, Matthias Brühlmeier, P. August Schubiger   +11 more
openalex   +2 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Next-Generation Sequencing in Oncology-A Guiding Compass for Targeted Therapy and Emerging Applications. [PDF]

Int J Mol Sci
Galeș LN, Păun MA, Butnariu I, Simion L, Manolescu LSC, Trifănescu OG, Anghel RM.   +6 more
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Peptide Aptamer-Paclitaxel Conjugates for Tumor Targeted Therapy. [PDF]

Pharmaceutics
Shen X, Ma Y, Luo H, Abdullah R, Pan Y, Zhang Y, Zhong C, Zhang B, Zhang G.   +8 more
europepmc   +1 more source

Targeting Therapy Using a Monoclonal Antibody against Tumor Vascular Endothelium

, 2000
Shin‐ichi Tsunoda, Y Tsutsumi, S Nakagawa, Tadanori Mayumi   +3 more
openalex   +2 more sources