Results 91 to 100 of about 248,862 (294)

A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale [PDF]

, 2009
In this era of complete genomes, our knowledge of neuroanatomical circuitry remains surprisingly sparse. Such knowledge is however critical both for basic and clinical research into brain function. Here we advocate for a concerted effort to fill this gap,
A MacKenzie-Graham, A Reiner, A Vercelli, A Visel, Allan Jones, AM Hattox, Arthur W. Toga, AW Toga, AY Hardan, B Egaas, B Horwitz, BL Davidson, Brett D. Mensh, Bruce W. Stillman, C Gustafson, C Kobbert, Caizhi Wu, CL Veenman, Claus C. Hilgetag, Clifford B. Saper, CR Gerfen, D Atasoy, DA Benson, Daniel G. Herrera, David C. Van Essen, David Kleinfeld, DC Van Essen, DC Van Essen, DL Sparks, E Miyashita, ED Jarvis, Edward G. Jones, EM Callaway, ES Lein, ET Bullmore, F Castelli, F Crick, G Aston-Jones, H Markram, Hans C. Breiter, Harvey J. Karten, HC Breiter, Helen Barbas, Hemant Bokil, Henry A. Lester, Hollis T. Cline, IR Wickersham, J DeFalco, J Dejerine, J Panksepp, J Panksepp, Jaak Panksepp, James D. Watson, Jason W. Bohland, JD Schmahmann, Jeremy D. Schmahmann, JF Démonet, JG Bjaalie, JG Bjaalie, JG Bjaalie, JG White, JL Lanciego, JM Lin, John C. Doyle, John M. Lin, Joseph L. Price, Joseph Safdieh, K Oishi, K Wernicke, Karel Svoboda, KE Stephan, KE Stephan, L Ng, L Stein, Larry W. Swanson, LM Coolen, M Bota, M Bota, M Bota, M Murias, MA Just, MD Johnson, MI Ekstrand, Michael Hawrylycz, Mihail Bota, MJ Swift, N Geschwind, Nicholas D. Schiff, O Sporns, Olaf Sporns, Partha P. Mitra, Peter J. Freed, PH Luppi, PJ Broser, R Kotter, R Kotter, Ralph J. Greenspan, RH Güting, RM Kelly, Rolf Kötter, RW Baughman, S Folstein, S Lillehaug, S Mikula, Shawn Mikula, Suzanne N. Haber, U Burgel, U Frith, V Grinevich, Z. Josh Huang   +109 more
core   +9 more sources

Mycotoxin exposure assessments in a multi-center European validation study by 24-hour dietary recall and biological fluid sampling [PDF]

, 2020
The European Food Consumption Validation (EFCOVAL) project includes 600 men and women from Belgium, the Czech Republic, France, the Netherlands, and Norway, who had given serum and 24-hour urine samples, and completed 24-hour dietary recall (24-HDR ...
Abbeddou, Souheila, Arcella, Davide, Claeys, Liesel, De Boevre, Marthe, De Keyzer, Willem, De Ruyck, Karl, De Saeger, Sarah, De Vries, Jeanne, Huybrechts, Inge, Ocke, Marga, Ruprich, Jiri, Yang, Shupeng   +11 more
core   +1 more source

ACTTS3 Encoding a Polyketide Synthase Is Essential for the Biosynthesis of ACT-Toxin and Pathogenicity in the Tangerine Pathotype of Alternaria alternata

Molecular Plant-Microbe Interactions, 2010
The tangerine pathotype of Alternaria alternata produces host-selective ACT-toxin and causes Alternaria brown spot disease of tangerine and tangerine hybrids.
Y. Miyamoto, A. Masunaka, T. Tsuge, M. Yamamoto, K. Ohtani, T. Fukumoto, K. Gomi, T. L. Peever, Y. Tada, K. Ichimura, K. Akimitsu   +10 more
doaj   +1 more source

Rhomboid Enhancer Activity Defines a Subset of Drosophila Neural Precursors Required for Proper Feeding, Growth and Viability. [PDF]

PLoS ONE, 2015
Organismal growth regulation requires the interaction of multiple metabolic, hormonal and neuronal pathways. While the molecular basis for many of these are well characterized, less is known about the developmental origins of growth regulatory structures
Amy L Gresser, Lisa M Gutzwiller, Mackenzie K Gauck, Volker Hartenstein, Tiffany A Cook, Brian Gebelein   +5 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Clostridioides difficile’s virulence requires efficient holin-mediated toxin secretion

iScience
Summary: The human pathogen Clostridioides difficile causes pseudomembranous colitis through release of the potent TcdA and TcdB toxins. These toxins lack canonical N-terminal secretion signal sequences for translocation across the bacterial membrane ...
Nicholas V. DiBenedetto, Marine Oberkampf, Aline Crouzols, Laura Cersosimo, Vladimir Yeliseyev, Lynn Bry, Johann Peltier, Bruno Dupuy   +7 more
doaj   +1 more source

Mycoplasma pneumoniae Community-Acquired Respiratory Distress Syndrome Toxin Uses a Novel KELED Sequence for Retrograde Transport and Subsequent Cytotoxicity

mBio, 2018
Mycoplasma pneumoniae is an atypical bacterium that causes respiratory illnesses in humans, including pharyngitis, tracheobronchitis, and community-acquired pneumonia (CAP).
Kumaraguruparan Ramasamy, Sowmya Balasubramanian, Krishnan Manickam, Lavanya Pandranki, Alexander B. Taylor, P. John Hart, Joel B. Baseman, T. R. Kannan   +7 more
doaj   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity. [PDF]

, 2018
Regulatory T cells (Tregs) are critical for maintaining immune homeostasis, but their presence in tumor tissues impairs anti-tumor immunity and portends poor prognoses in cancer patients.
Abnousian, Arbi, Bluestone, Jeffrey A, DuPage, Michel, Fong, Lawrence, Harwin, Tory, Mahuron, Kelly, Pagani, Massimiliano, Pai, Chien-Chun, Quiros, Jason, Ranzani, Valeria, Rosenblum, Michael D, Silveria, Stephanie, Van Gool, Frederic, Wang, David, Young, Arabella   +14 more
core   +2 more sources