Results 251 to 260 of about 248,862 (294)
Neurosurgery to restore function in cerebral palsy: current practice and emerging therapies. [PDF]
Front Rehabil SciSankar A +5 more
europepmc +1 more source
Development of a Human IgG1 Monoclonal Antibody Targeting Transferrin Receptor 1 for Antitumor Drug Delivery. [PDF]
Antibodies (Basel)Ji T, Zong Z, Gong N, Yan M, Chen S.
europepmc +1 more source
Precision nutrition guided by genomic and functional assessments in postmenopause: a case report. [PDF]
Front NutrNoland J.
europepmc +1 more source
Biodistribution of the Bombesin Receptor-Targeted Radiopharmaceutical Precursor BBN/C1-C2 in a Prostate Cancer Model. [PDF]
Sovrem Tekhnologii MedBeloborodov EA +6 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Diphtheria toxin-based targeted toxins that target glioblastoma multiforme
Toxin Reviews, 2014AbstractTargeted toxins (TTs) are compounds that bind cell surface receptors overexpressed on cancer cells. After the molecule enters the cell, the toxin component migrates to the ribosomes where it blocks protein synthesis killing the cell. Most of these proteins are recombinant and contain a carrier ligand or antibody attached to a modified bacterial
Yan Michael Li
exaly +2 more sources
Diphtheria toxin-based targeted toxin therapy for brain tumors
Journal of Neuro-Oncology, 2013Targeted toxins (TT) are molecules that bind cell surface antigens or receptors such as the transferrin or interleukin-13 receptor that are overexpressed in cancer. After internalization, the toxin component kills the cell. These recombinant proteins consist of an antibody or carrier ligand coupled to a modified plant or bacterial toxin such as ...
Yan Michael Li, Daniel A Vallera
exaly +3 more sources
Angewandte Chemie International Edition, 2012
AbstractProtein toxins constitute the main virulence factors of several species of bacteria and have proven to be attractive targets for drug development. Lead candidates that target bacterial toxins range from small molecules to polymeric binders, and act at each of the multiple steps in the process of toxinâmediated pathogenicity.
Mattias E, Ivarsson +2 more
openaire +4 more sources
AbstractProtein toxins constitute the main virulence factors of several species of bacteria and have proven to be attractive targets for drug development. Lead candidates that target bacterial toxins range from small molecules to polymeric binders, and act at each of the multiple steps in the process of toxinâmediated pathogenicity.
Mattias E, Ivarsson +2 more
openaire +4 more sources
Current Protocols in Neuroscience, 2001
AbstractMolecular neurosurgery can be used to make selective neural lesions by targeting cytotoxins to specific populations of neurons based on their common expression of a particular surface molecule. The targeted toxins employed in this unit consist of a targeting moiety (vector) and an effector moiety (cytotoxin). In all cases discussed in this unit,
R G, Wiley, D A, Lappi
openaire +2 more sources
AbstractMolecular neurosurgery can be used to make selective neural lesions by targeting cytotoxins to specific populations of neurons based on their common expression of a particular surface molecule. The targeted toxins employed in this unit consist of a targeting moiety (vector) and an effector moiety (cytotoxin). In all cases discussed in this unit,
R G, Wiley, D A, Lappi
openaire +2 more sources
Advanced Drug Delivery Reviews, 2003
Although only recently applied to the study of nociception, 'molecular neurosurgery', producing highly selective neural lesions using targeted cytotoxins, has proven a valuable tool for analysis of nociceptive systems and promises to yield much more information on the role of specific types of neurons in pain perception and possibly new pain therapies.
Ronald G, Wiley, Douglas A, Lappi
openaire +2 more sources
Although only recently applied to the study of nociception, 'molecular neurosurgery', producing highly selective neural lesions using targeted cytotoxins, has proven a valuable tool for analysis of nociceptive systems and promises to yield much more information on the role of specific types of neurons in pain perception and possibly new pain therapies.
Ronald G, Wiley, Douglas A, Lappi
openaire +2 more sources
Journal of Oncology Pharmacy Practice, 1999
Objective. Current modalities used in the treatment of cancer often cause unacceptable damage to normal tissue. Toxins targeted toward tumor cells by antibodies or growth factors have the potential to selectively kill tumor cells while leaving normal tissue intact.
M W J den Brok +3 more
openaire +1 more source
Objective. Current modalities used in the treatment of cancer often cause unacceptable damage to normal tissue. Toxins targeted toward tumor cells by antibodies or growth factors have the potential to selectively kill tumor cells while leaving normal tissue intact.
M W J den Brok +3 more
openaire +1 more source