Results 121 to 130 of about 3,224,482 (340)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Investigación con el sistema da Vinci® en el Hospital St Mary’s de Londres Evaluation of the use the da Vinci system at St. Mary's Hospital in London

Revista Colombiana de Cirugía, 2005
Hipótesis: El sistema robótico da Vinci™ permite superar las limitaciones que impone al cirujano la cirugía mínimamente invasora en términos de destreza, control del campo operatorio y ergonomía.
Juan David Hernández, Aristotelis Dosis, Fernando Bello, Dorothy Wang, Joao Borelli, Ara Darzi   +5 more
doaj  

AED: Altruism, Excellence, and Duty—A Professionalism Module for Emergency Medicine

MedEdPORTAL, 2011
This is a 2-hour module designed for emergency medicine residents that summarizes the concepts of professionalism into three core values of altruism, excellence, and duty.
Edward Callahan, Karen Marcdante
doaj   +1 more source

impact of supplementary short rest breaks on task performance – A meta-analysis [PDF]

, 2016
Johannes Wendsche, Andrea Lohmann-Haislah, Jürgen Wegge   +2 more
openalex   +1 more source

Improving the Performance of Individually Calibrated SSVEP-BCI by Task- Discriminant Component Analysis [PDF]

, 2021
Bingchuan Liu, Xiaogang Chen, Nanlin Shi, Yijun Wang, Shangkai Gao, Xiaorong Gao   +5 more
openalex   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Acquisition and production of skilled behavior in dynamic decision-making tasks [PDF]

This status report consists of a thesis entitled 'Ecological Task Analysis: A Method for Display Enhancements.' Previous use of various analysis processes for the purpose of display interface design or enhancement has run the risk of failing to improve ...
Kirlik, Alex, Kossack, Merrick Frank
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Investigation of independence in the tasks involving the use of public transportation in patients with subacute stroke

Journal of Rehabilitation Medicine
Objective: To clarify the percentage of stroke patients who are independent in performing tasks involved in public transportation use and problems faced while doing so. Design: Single-institution retrospective study.
Shin Kitamura, Yohei Otaka, Kazuki Ushizawa, Seigo Inoue, Sachiko Sakata, Kunitsugu Kondo   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source