Results 101 to 110 of about 478,616 (367)
Extraoral bitter taste receptors in health and disease
The Journal of General Physiology, 2017 Bitter taste receptors (TAS2Rs or T2Rs) belong to the superfamily of seven-transmembrane G protein–coupled receptors, which are the targets of >50% of drugs currently on the market.
P. Lu +3 more
semanticscholar +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Inflammation arising from obesity reduces taste bud abundance and inhibits renewal
PLoS Biology, 2018 Despite evidence that the ability to taste is weakened by obesity and can be rescued with weight loss intervention, few studies have investigated the molecular effects of obesity on the taste system.
Andrew Kaufman +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Tractography indicates lateralized differences between trigeminal and olfactory pathways
NeuroImage, 2022 Odorous sensations are based on trigeminal and olfactory perceptions. Both trigeminal and olfactory stimuli generate overlapping as well as distinctive activations in the olfactory cortex including the piriform cortex.
Divesh Thaploo +4 more
doaj
Mixture-of-tastes Models for Representing Users with Diverse Interests [PDF]
arXiv, 2017 Most existing recommendation approaches implicitly treat user tastes as unimodal, resulting in an average-of-tastes representations when multiple distinct interests are present. We show that appropriately modelling the multi-faceted nature of user tastes through a mixture-of-tastes model leads to large increases in recommendation quality.
arxiv
Critical reviews in food science and nutrition, 2018 Food preferences and dietary habits are heavily influenced by taste perception. There is growing interest in characterizing taste preferences based on genetic variation. Genetic differences in the ability to perceive key tastes may impact eating behavior
E. Chamoun +7 more
semanticscholar +1 more source
Cell, 2020 Biology is entering a new era in which techniques honed in model systems can be applied to the expanding array of organisms with sequenced genomes. In this issue of Cell, van Giesen et al. (2020) characterize the molecular foundation of the touch-taste sensory system in octopus suckers.
openaire +4 more sources
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Recent advances in taste transduction and signaling
F1000Research, 2019 In the last few years, single-cell profiling of taste cells and ganglion cells has advanced our understanding of transduction, encoding, and transmission of information from taste buds as relayed to the central nervous system.
S. Kinnamon, T. Finger
semanticscholar +1 more source