Results 141 to 150 of about 6,869 (288)

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo   +5 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

A Molecular Analysis of Signaling Pathways during Taste Bud Differntiation in Axolotls

open access: yes, 2020
The Notch Pathway is a key signaling pathway that plays a major role in the development and differentiation of many cells. Its function has been identified in the prognosis of several diseases such as cerebral autosomal dominant arteriopathy with ...
Jennings, Tiara
core  

Meyna grisea (King & Gamble) Robyns and Meyna peltata Robyns (Rubiaceae: Vanguerieae) – a new record of two ethnobotanically significant fruit trees from Manipur, India

open access: yesNordic Journal of Botany, EarlyView.
Meyna grisea and M. peltata, two new records from Imphal Valley, Manipur, India, characterised by a capitate stigma with 4–5 divergent, spreading lobes on a globose base, and a prominent peltate stigma, respectively, are described and illustrated here. Photographs, key to the species, along with their coordinates and diagnostic characters in comparison
Pallavi B. Dhal   +3 more
wiley   +1 more source

Cybianthus anthuriophyllus (Primulaceae), a new record for the flora of Colombia: distribution modeling and conservation assessment

open access: yesNordic Journal of Botany, EarlyView.
Cybianthus anthuriophyllus (Primulaceae) was previously known from eastern Ecuador and northern Peru. Here we document the first confirmed occurrences of this species in Colombia and develop a distribution model based on collections from the Andean–Amazonian foothills of Caquetá, Cauca, and Putumayo departments, in order to clarify its conservation ...
David Hoyos   +4 more
wiley   +1 more source

Inequalities in intraspecific plant–lemur interactions drive seed dispersal patterns

open access: yesOikos, EarlyView.
Biotic interactions occur between individuals and accumulate to shape species‐level interaction structure across a community. Skewed interaction structures, where a few individuals are highly connected and most have few interactions, are increasingly identified at the individual‐level.
Jadelys Tonos   +2 more
wiley   +1 more source

Taste bud of the tongue

open access: yes
Scheme electronmicroscopy. Generally a taste bud is composed of about 20 to 70 spindle-shaped epithelial cells. Slender type I cell (\u27Dark\u27 cell) and oval shaped type II cell (\u27Light\u27 cell) with a pale, round nucleus with their apices end in ...
Poels, Lambert G.
core  

Enabling effective urban green space stewardship through planning: A qualitative comparative analysis in Southwest England

open access: yesPeople and Nature, EarlyView.
Abstract Amid increasing urbanisation and biodiversity decline, ‘effective stewardship’ of urban green space (UGS) is a complex but critical nature‐based solution for long‐term environmental, social and economic gain. Combining stewardship and sense‐of‐place frameworks with European nature‐based solutions guidance, we investigate which social and ...
Fay Kahane   +2 more
wiley   +1 more source

A comprehensive checklist of Mediterranean wild edible plants: Diversity, traditional uses, and knowledge gaps

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The use of wild edible plants and the traditional knowledge associated with them are rapidly disappearing across the Mediterranean, with serious consequences for biodiversity, cultural heritage, and regional food security. This study compiles and organizes fragmented information to create the first comprehensive catalogue of these plants across the ...
Benedetta Gori   +5 more
wiley   +1 more source

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