Results 201 to 210 of about 268,731 (242)

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2‐KLF4

open access: yesCell Proliferation, EarlyView.
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Wenrui Zeng   +8 more
wiley   +1 more source

Depicting the Immunological Landscape of Basal Cell Carcinoma Subtypes

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Anti‐PD‐1 response has been associated with higher PD‐1 ligand (PD‐L1) expression levels in different cancer types. Cemiplimab, an anti‐PD‐1 antibody, has been shown to induce a response rate of 31% and 22% in patients with locally advanced basal cell carcinoma (BCC) and metastatic BCC respectively, who have progressed or are ...
Isabella Dommann   +9 more
wiley   +1 more source

Two Metschnikowia nectar yeast species have similar volatile profiles but elicit differential foraging in bee pollinators

open access: yesEcological Entomology, EarlyView.
Yeasts that specialize in flower nectar play an important role in pollination ecology. Metschnikowia reukaufii and Metschnikowia koreensis were the most prevalent nectar yeasts found in our field sites. Bee pollinators exhibited different behavioural responses to nectar yeasts in field experiments. Bees visited more flowers with M.
M. Elizabeth Moore   +8 more
wiley   +1 more source

Honeybees directly outcompete other flower visitors through interference competition on shared resource

open access: yesEcological Entomology, EarlyView.
The outcomes of encounters between honeybees and other flower visitors were observed on two plant species. Pollinators either win, lose or share a resource. Competitive interactions led to greater than expected ‘wins’ for honeybees. The honeybee displaced or gave chase when interacting with another pollinator in at least 20% of winning outcomes ...
Victoria A. Buckle   +3 more
wiley   +1 more source

Bitter taste receptor T2R7 and umami taste receptor subunit T1R1 are expressed highly in Vimentin-negative taste bud cells in chickens. [PDF]

open access: yesBiochem Biophys Res Commun, 2019
Yoshida Y   +9 more
europepmc   +1 more source

The Innocence of Imagination?

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract According to a widely held view both within and outside philosophy, imagination is innocent in the sense that it does not influence what we think and do. Hence, we can let our imagination wander anywhere. There are two ways of pushing back against this ‘innocence of imagination’ claim.
Bence Nanay
wiley   +1 more source

Insulin Is Transcribed and Translated in Mammalian Taste Bud Cells.

open access: yesEndocrinology, 2018
Doyle ME   +9 more
europepmc   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs   +9 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

open access: yesThe FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén   +11 more
wiley   +1 more source

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