Results 71 to 80 of about 436,774 (328)

Calcitonin Gene-Related Peptide Reduces Taste-Evoked ATP Secretion from Mouse Taste Buds

open access: yesJournal of Neuroscience, 2015
Immunoelectron microscopy revealed that peripheral afferent nerve fibers innervating taste buds contain calcitonin gene-related peptide (CGRP), which may be as an efferent transmitter released from peripheral axon terminals. In this report, we determined
Anthony Y. Huang, Sandy Y Wu
semanticscholar   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

FGF- and SHH-based molecular signals regulate barbel and craniofacial development in catfish

open access: yesZoological Letters, 2019
Background Catfish (Siluriformes) are characterized by unique morphologies, including enlarged jaws with movable barbels and taste buds covering the entire body surface. Evolution of these characteristics was a crucial step in their adaptive radiation to
Tatsuya Itoyama   +5 more
doaj   +1 more source

Smell and taste disorders in COVID-19: From pathogenesis to clinical features and outcomes

open access: yesNeuroscience Letters, 2021
Patients with COVID-19 often complain of smell and taste disorders (STD). STD emerge early in the course of the disease, seem to be more common in SARS-CoV-2 infection than in other upper respiratory tract infections, and could in some cases persist for ...
A. Mastrangelo, M. Bonato, P. Cinque
semanticscholar   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds

open access: yesCancer Medicine, 2014
Vismodegib, a highly selective inhibitor of hedgehog (Hh) pathway, is an approved treatment for basal‐cell carcinoma. Patients on treatment with vismodegib often report profound alterations in taste sensation.
Hyekyung Yang   +3 more
semanticscholar   +1 more source

Connexin 43‐Enriched Vesicles Improve Synchronization in hiPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Plasma membrane‐derived Connectosomes enriched in connexin‐43 are produced from donor hiPSCs and applied to hiPSC‐derived cardiomyocytes (hiPSC‐CMs). Connexin‐43 channels on Connectosomes remain functional, strengthening intercellular electrochemical coupling and increasing network synchronization over time.
Nima Momtahan   +8 more
wiley   +1 more source

Ontogeny of feeding and digestive system in cobitidian fish Noemacheilus montanus (McClelland)

open access: yesEnvironment Conservation Journal, 2012
Noemacheilus montanus is a bottom feeder water tracer fish of Himalayan region. The fish moves within the minute water capillaries in the mountain region and inhabited in small tributaries of hill stream.
S. N. Bahuguna   +3 more
doaj   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

open access: yesAdvanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang   +10 more
wiley   +1 more source

Differential expression of a BMP4 reporter allele in anterior fungiform versus posterior circumvallate taste buds of mice

open access: yesBMC Neuroscience, 2010
Background Bone Morphogenetic Protein 4 (BMP4) is a diffusible factor which regulates embryonic taste organ development. However, the role of BMP4 in taste buds of adult mice is unknown. We utilized transgenic mice with LacZ under the control of the BMP4
Barlow Linda A, Nguyen Ha M
doaj   +1 more source

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