Results 31 to 40 of about 1,021,795 (377)

Adenosine A_2A receptor binding profile of two antagonists, ST1535 and KW6002: consideration on the presence of atypical adenosine A_2A binding sites

Frontiers in Psychiatry, 2010
Adenosine A2A receptors seem to exist in typical (more in striatum) and atypical (more in hippocampus and cortex) subtypes. In the present study, we investigated the affinity of two adenosine A2A receptor antagonists, ST1535 [2 butyl -9-methyl-8-(2H-1,2 ...
Teresa Riccioni, Fabiana Leonardi, Franco Borsini   +2 more
doaj   +1 more source

A Co-Operative Autonomous Offshore System for Target Detection Using Multi-Sensor Technology

Remote Sensing, 2020
This article studies the design, modeling, and implementation challenges for a target detection algorithm using multi-sensor technology of a co-operative autonomous offshore system, formed by an unmanned surface vehicle (USV) and an autonomous underwater
Jose Villa, Jussi Aaltonen, Sauli Virta, Kari T. Koskinen   +3 more
doaj   +1 more source

Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography

JAMA Neurology, 2022
This cross-sectional study of 2 observational cohorts investigates if phosphorylated tau biomarkers are more associated with the presence of cerebral β-amyloidosis or tau neurofibrillary tangle aggregation.
J. Therriault, Marie-Christine Vermeiren, S. Servaes, C. Tissot, N. Ashton, A. Benedet, T. Karikari, J. Lantero-Rodríguez, W. Brum, Firoza Z. Lussier, G. Bezgin, J. Stevenson, N. Rahmouni, Peter Kunach, Y. Wang, J. Fernandez-Arias, Kely Monica Quispialaya Socualaya, A. Macedo, J. Ferrari-Souza, P. Ferreira, B. Bellaver, D. Leffa, E. Zimmer, P. Vitali, J. Soucy, G. Triana-Baltzer, H. Kolb, T. Pascoal, P. Saha-Chaudhuri, S. Gauthier, H. Zetterberg, K. Blennow, P. Rosa-Neto   +32 more
semanticscholar   +1 more source

Tau here, tau there, tau almost everywhere: Clarifying the distribution of tau in the adult CNS

Cytoskeleton, 2023
AbstractThe microtubule‐associated protein tau has gained significant attention over the last several decades primarily due to its apparent role in the pathogenesis of several diseases, most notably Alzheimer's disease. While the field has focused largely on tau's potential contributions to disease mechanisms, comparably less work has focused on normal
openaire   +2 more sources

Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease

Neural Regeneration Research, 2022
Alzheimer’s disease is a neurodegenerative disease that accounts for most of the 50-million dementia cases worldwide in 2018. A large amount of evidence supports the amyloid cascade hypothesis, which states that amyloid-beta accumulation triggers tau ...
Alejandro R Roda, Gabriel Serra-Mir, Laia Montoliu‐Gaya, Lidia Tiessler, S. Villegas   +4 more
semanticscholar   +1 more source

The tau code [PDF]

Frontiers in Aging Neuroscience, 2009
In this short review, I will focus on how a unique tau gene may produce many tau isoforms through alternative splicing and how the phosphorylation of these isoforms by different kinases may affect their activity and behaviour. Indeed, each of the different tau isoforms may play a distinct role under both physiological and pathological conditions. Thus,
openaire   +4 more sources

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Lifetime Ratios of Beauty Hadrons at the Next-to-Leading Order in QCD [PDF]

, 2002
We compute the next-to-leading order QCD corrections to spectator effects in the lifetime ratios of beauty hadrons. With respect to previous calculations, we take into account the non vanishing value of the charm quark mass. We obtain the predictions tau(
Baek, Bagan, Bagan, Bagan, Bagan, Becirevic, Beneke, Beneke, Beneke, Bigi, Bigi, Bloch, Buras, Buras, C. Tarantino, Chay, Cheng, Chernyak, Chetyrkin, Ciuchini, Ciuchini, Ciuchini, Colangelo, Di Pierro, Di Pierro, Di Pierro, Di'Lieto, Doria, E. Franco, F. Mescia, Falk, Gimenez, Ho-kim, Huang, Khoze, Mertig, Misiak, Neubert, Neubert, Nir, Pirjol, Tarasov, Tarasov, Uraltsev, V. Lubicz   +44 more
core   +3 more sources

Data‐driven performance metrics for neural network learning

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri, Mauro Gaggero, Marcello Sanguineti   +2 more
wiley   +1 more source

The initial stage of the development of the semi-free population of the Przewalski's horse in the Orenburg State Nature Reserve (Russia)

Nature Conservation Research: Заповедная наука, 2019
The Joint Directorate of the State Nature Reserves «Orenburg» and «Shaitan-Tau» (later – FSFI «Orenburg Reserves») elaborated the Programme on establishing a semi-free population of the Przewalski's horse in the Orenburg State Nature Reserve (Russia). It
Rafilia T. Bakirova, Tatjana L. Zharkikh, Evgeniy A. Bulgakov   +2 more
doaj   +1 more source