Results 81 to 90 of about 854,024 (332)

LPS-induced serum TNF production and lethality in mice: effect of L-carnitine and some acyl-derivatives

open access: yesMediators of Inflammation, 1993
The effect of L-carnitine and some of its acyl derivatives on serum TNF production and lethality in a murine experimental endotoxin shock model was investigated. In some instances, serum IL-6 production was also evaluated.
Vito Ruggiero   +5 more
doaj   +1 more source

Mean Platelet Volume in Neonatal Sepsis: Meta-Analysis of Observational Studies

open access: yesChildren, 2022
Introduction: Early onset neonatal sepsis (EONS), particularly in preterm sepsis, is a potentially fatal issue. Evaluation of mean platelet volume (MPV) as an EONS predictor was the goal.
Carlos J. Toro-Huamanchumo   +6 more
doaj   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

Sensitivity of T2KK to non-standard interactions

open access: yes, 2010
Assuming only the non-zero electron and tau neutrino components $\epsilon_{ee}$, $\epsilon_{e\tau}$, $\epsilon_{\tau\tau}$ of the non-standard matter effect and postulating the atmospheric neutrino constraint $\epsilon_{\tau\tau}=|\epsilon_{e\tau}|^2/(1+\
Bandyopadhyay   +8 more
core   +1 more source

Evidence for the Appearance of Atmospheric Tau Neutrinos in Super-Kamiokande [PDF]

open access: yes, 2013
Super-Kamiokande atmospheric neutrino data were fit with an unbinned maximum likelihood method to search for the appearance of tau leptons resulting from the interactions of oscillation-generated tau neutrinos in the detector. Relative to the expectation
A. Hocker   +114 more
core   +2 more sources

Tau physics and Tau-Charm factories

open access: yesNuclear Physics B - Proceedings Supplements, 1993
The present knowledge of the τ lepton and the prospects for future improvements are discussed.
openaire   +3 more sources

Tau and tauopathies

open access: yesBrain Research Bulletin, 2016
Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly understood; current nosological concepts are largely based on these molecular signatures of protein aggregates which also provide valuable tools for neuropathological ...
Jens Stieler, Max Holzer, Thomas Arendt
openaire   +3 more sources

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

open access: yesFEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal   +2 more
wiley   +1 more source

A distinct plasmablast and naïve B-cell phenotype in primary immune thrombocytopenia

open access: yesHaematologica, 2016
Primary immune thrombocytopenia is an autoimmune disorder in which platelet destruction is a consequence of both B- and T-cell dysregulation. Flow cytometry was used to further characterize the B- and T-cell compartments in a cross-sectional cohort of 26
Shaun M. Flint   +8 more
doaj   +1 more source

Plasma tau complements CSF tau and P‐tau in the diagnosis of Alzheimer's disease

open access: yesAlzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019
AbstractIntroductionPlasma tau may be an accessible biomarker for Alzheimer's disease (AD), but the correlation between plasma and cerebrospinal fluid (CSF) tau and the value of combining plasma tau with CSF tau and phospho‐tau (P‐tau) are still unclear.MethodsPlasma‐tau, CSF‐tau, and P‐tau were measured in 97 subjects, including elderly cognitively ...
Yi Li   +11 more
openaire   +5 more sources

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