Results 81 to 90 of about 219,363 (324)
A new approach to convolution and semi-direct products of groups [PDF]
arXiv, 2012 Let $H$ and $K$ be locally compact groups and $\tau:H\to Aut(K)$ be a continuous homomorphism and also let $G_\tau=H\ltimes_\tau K$ be the semi-direct product of $H$ and $K$ with respect to $\tau$. We define left and also right $\tau$-convolution on $L^1(G_\tau)$ such that $L^1(G_\tau)$ with respect to each of them is a Banach algebra. Also we define $\
arxiv
Brain Research Bulletin, 2016 Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly understood; current nosological concepts are largely based on these molecular signatures of protein aggregates which also provide valuable tools for neuropathological ...
Jens Stieler, Max Holzer, Thomas Arendt
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Intracellular and extracellular tau [PDF]
Frontiers in Neuroscience, 2010 In this short review is described the toxicity of modified intracellular tau and that of extracellular tau that could be released into the extracellular space after neuron death.
Jesús Avila, Jesús Avila
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Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez +15 more
wiley +1 more source
The Tau Lepton and the Search for New Elementary Particle Physics [PDF]
arXiv, 1998 This Fifth International WEIN Symposium is devoted to physics beyond the standard model. This talk is about tau lepton physics, but I begin with the question: do we know how to find new physics in the world of elementary particles? This question is interwoven with the various tau physics topics.
arxiv
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective We measured clinical and quantitative MRI outcome measures in CMT1A to assess long‐term responsiveness, establish longitudinal validity and assess MRI as a bridging biomarker. Methods Twenty patients with CMT1A and 20 matched controls underwent MRI, myometry and clinical assessments up to four times over mean 4‐year follow‐up ...
Matthew R. B. Evans +8 more
wiley +1 more source
Estimates of solutions to the linear Navier-Stokes equation [PDF]
arXiv, 2020 The linear Navier-Stokes equations in three dimensions are given by: $u_{it}(x,t)-\rho \triangle u_i(x,t)-p_{x_i}(x,t)=$ $w_i(x,t)$ , $div \textbf{u}(x,t)=0,i=1,2,3$ with initial conditions: $\textbf{u}|_{(t=0)\bigcup\partial\Omega}=0$. The Green function to the Dirichlet problem $\textbf{u}|_{(t=0)\bigcup\partial\Omega}=0$ of the equation $u_{it}(x,t)-
arxiv
Characteristics of Tau Oligomers [PDF]
Frontiers in Neurology, 2013 In Alzheimer disease (AD) and other tauopathies, microtubule-associated protein tau becomes hyperphosphorylated, undergoes conformational changes, aggregates, eventually becoming neurofibrillary tangles (NFTs). As accumulating evidence suggests that NFTs themselves may not be toxic, attention is now turning toward the role of intermediate tau oligomers
Yan Ren, Naruhiko Sahara
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ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective We performed a pilot screen to assess the utility of the NULISA™ (Nucleic‐acid‐Linked Immuno‐Sandwich Assay) platform in the identification of amyotrophic lateral sclerosis (ALS) biomarkers. Methods Plasma from 86 individuals (48 ALS, 18 asymptomatic C9orf72 repeat expansion carriers (AsymC9), and 20 healthy controls) was analyzed ...
Eleanor V. Thomas +10 more
wiley +1 more source
Frontiers in Neurology, 2013 The nature of "toxic" tau in Alzheimer's disease (AD) has been unclear. During pathogenesis, the importance of tau oligomerization vs. tau phosphorylation is controversial and the investigation of both remains critical toward defining the "toxicity" of tau.
Gloria Lee +3 more
openaire +3 more sources