Results 121 to 130 of about 162,388 (137)

Mechanistic Studies of Taxadiene and Abietadiene Synthases

2001
Abstract : Investigation aimed at understanding the enzymatic mechanism of the two diterpene cyclases, taxadiene and abietadiene synthase, may yield an alternative approach to combinatorial chemistry in the search for new and improved chemotherapeutic and antibiotic drugs.
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[Combinational expression of geranylgeranyl diphosphate synthase and taxadiene synthase in Coprinopsis cinerea].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2015
Taxa-4(5),11(12)-diene is the precursor for paclitaxel biosynthesis. The diterpenoid paclitaxel (marketed as Taxol), a plant secondary metabolite isolated from yew, is an effective drug widely used in the treatment of numerous cancers. However, further application of taxol has been restricted due to its low yield in plants and the difficulties in ...
Linfeng, You, Haixing, Yang, Junfang, Lin, Zhiwei, Ye, Liqiong, Guo, Yanhua, Xin   +5 more
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[Cloning of taxadiene synthase cDNA from the cell line of Taxus cuspidata].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2000
Taxadiene synthase plays an important role in taxol biosynthesis. RT-PCR was used for cloning taxadiene synthase cDNA fragment from the cells of T. cuspidata. The cDNA was cloned into vector pGEM and transformed to E. coli J M109. The cloned cDNA named pCBMZ was further confirmed by Southern blotting assay and was sequenced.
G W, Hu, Z, Ma, T Y, Wen, Y J, Yuan
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Purification and Biochemical Characterization of Taxadiene Synthase from Bacillus koreensis and Stenotrophomonas maltophilia

Scientia Pharmaceutica, 2021
Mahmoud Sitohy, Basel Sitohy, Maher Fathalla   +2 more
exaly  

Taxane production in hairy roots of Taxus x media var. Hicksii carrying taxadiene synthase gene

Planta Medica, 2010
Syklowska-Baranek, Katarzyna, Bonfill, Mercedes, Pietrosiuk, Agnieszka, Cusido, Rosa, Palazon, Jawier   +4 more
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Taxadiene synthase

2010
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Natural and engineered production of taxadiene with taxadiene synthase

Biotechnology and Bioengineering, 2015
Sameh S M Soliman
exaly  

TAXADIENE SYNTHASE TCTS2, CODING NUCLEOTIDE SEQUENCE AND USE THEREOF

2022
YAN JIANBIN, GOU JUNBO, LIAO QINGGANG, LIANG HAIFEI, LI CHONG, DU RAN, XIONG XINGYAO, HUANG SANWEN   +7 more
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Sobralene, a new sex-aggregation pheromone and likely shunt metabolite of the taxadiene synthase cascade, produced by a member of the sand fly Lutzomyia longipalpis species complex

Tetrahedron Letters, 2018
James Hamilton, Gerry Pattenden, Matthew Palframan   +2 more
exaly  

Taxadiene Synthase purification and Molecular Characterization in Podocarpus elongatus EFBL-NZM for an Enhanced Taxadiene biosynthesis, a Key Taxol Biosynthetic Intermediate

Bulletin of Faculty of Science, Zagazig University
Nabil Z. Mohamed, Lamis Shaaban, Samia safan   +2 more
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