Results 81 to 90 of about 1,290 (186)

Pacific Blue-Taxoids as Fluorescent Molecular Probes of Microtubules. [PDF]

Methods Mol Biol, 2022
Andres AE, Rane D, Peterson BR.
europepmc   +1 more source

Effect of 2′-OH acetylation on the bioactivity and conformation of 7-O-[N-(4′-fluoresceincarbonyl)-l-alanyl]taxol. A NMR-fluorescence microscopy study

, 1998
The relationship between conformation, 2′-OH acetylation, and bioactivity of two fluorescent taxoids has been investigated by a combination of NMR and fluorescence microscopy techniques.
Barbero, José Luis, Souto, André A., Abal, Miguel, Barasoain, Isabel, Evangelio, Juan A.   +4 more
core   +1 more source

Synthesis of New Generation Taxoid Anticancer Agents and Dendrimer-Based Multifunctional Conjugates for Tumor-Targeting Drug Delivery

, 2016
Cancer remains the second leading cause of death in the United States. Although tremendous efforts have been made in the area of cancer therapy, there is still no common cure for cancer.
Sun, Yi
core  

Docetaxel (Taxotere), a novel taxoid, in the treatment of advanced colorectal carcinoma: an EORTC Early Clinical Trials Group Study [PDF]

, 1994
Docetaxel (Taxotere), a new semisynthetic taxoid, is a potentially important chemotherapeutic agent for the treatment of cancer. Forty patients with bidimensionally measurable advanced adenocarcinoma of the colon were treated with docetaxel 100 mg m-2 ...
Dirix, L. Y., Le Bail, N., ten Bokkel Huinink, W. W., Wanders, S., Bruntsch, V., Pavlidis, N. A., Sternberg, C. N., Smyth, J. F., Kaye, S. B., Franklin, H.   +9 more
core  

Efficient Asymmetric Syntheses of β-Lactams Bearing a Cyclopropane or an Epoxide Moiety and Their Application to the Syntheses of Novel Isoserines and Taxoids

, 2016
Efficient Asymmetric Syntheses of β-Lactams Bearing a Cyclopropane or an Epoxide Moiety and Their Application to the Syntheses of Novel Isoserines and ...
Songnian Lin (2435152), Iwao Ojima (295240)   +1 more
core   +1 more source

Functions of Representative Terpenoids and Their Biosynthesis Mechanisms in Medicinal Plants. [PDF]

Biomolecules, 2023
Wang Q, Zhao X, Jiang Y, Jin B, Wang L.
europepmc   +1 more source

Design, synthesis and SAR study of Fluorine-containing 3rd-generation taxoids. [PDF]

Bioorg Chem, 2022
Wang C, Chen L, Sun Y, Guo W, Taouil AK, Ojima I.   +5 more
europepmc   +1 more source

Corrigendum to "Nanoemulsion formulation of a novel taxoid DHA-SBT-1214 Inhibits prostate cancer stem cell-induced tumor growth" [Cancer Lett. 2017 Aug 11;406:71-80]. [PDF]

Cancer Lett
Ahmad G, El Sadda R, Botchkina G, Ojima I, Egan J, Amiji M.   +5 more
europepmc   +1 more source

4 Metabolism and pharmacology of taxoids

, 1995
Publisher Summary This chapter presents metabolism and pharmacology of taxoids. Three main modifications occur in taxoids when they are introduced in the organism—namely, (1) epimerization, (2) hydrolysis, and (3) hydroxylation. After 72 h of incubation, the ratio of 7-epi-paclitaxel to paclitaxel varies from 0.36 to 0.48 in the cell and from 0.25 to
openaire   +1 more source

Toward Sustainable Paclitaxel Bioproduction: Plant Biology, Biosynthesis and Platform Engineering. [PDF]

Plants (Basel)
Zhang M, Xing X, Zhu H.
europepmc   +1 more source