Results 71 to 80 of about 1,290 (186)

MOESM10 of Comparative metabolomic analysis reveals the variations in taxoids and flavonoids among three Taxus species

open access: yes, 2019
Additional file 10: Table S3.
Chenjia Shen (630236)   +10 more
core   +1 more source

Synthesis and Biological Evaluation of Second and Third Generation of Taxoid Anticancer Agents

open access: yes, 2014
Cancer is a group of diseases leading by uncontrolled cell growth, and is responsible for approximately one in four deaths in the United States. While significant advancements have been made in chemotherapy, combating drug resistant strains have remained
Wang, Xin
core  

Docetaxel

open access: yes, 1997
Paclitaxel was the first taxoid to become available. It was found to be an active anticancer agent but with significant toxicity. Docetaxel is a semisynthetic taxoid and the next of a fast-expanding class of drugs.
Leahy, M, Howell, A; id_orcid
core   +2 more sources

Intervention effect of intermittent hand⁃foot hypothermia therapy with different temperatures on chemotherapy⁃induced peripheral neurotoxicity for breast cancer

open access: yesHuli yanjiu
ObjectiveTo evaluate the effect on chemotherapy⁃induced peripheral neurotoxicity(CIPN),hand and foot syndrome(HFS),and quality of life in breast cancer patients treated with intermittent hand and foot hypothermia at different temperatures.MethodsA total ...
LI Ran   +3 more
doaj  

The design, synthesis and biological evaluation of novel taxoid anticancer agents and their tumor-targeted drug conjugates

open access: yes, 2013
Cancer is the second leading cause of death in the United States and is responsible for one in eight deaths worldwide. Traditional chemotherapeutics target the processes involved in cell division and consequently produce dangerous and dose-limiting side ...
Seitz, Joshua
core  

Synthesis of New-Generation Taxoid and Taxoid-Based Tumor-Targeting Drug Conjugates

open access: yes, 2015
Cancer is a group of diseases characterized by uncontrolled growth and spread of abnormal cells, and it is the leading cause of death around the world.
Chen, Ying-Jen
core  

Part I. Design, synthesis and biological evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents., Part II. Development of novel taxoid-based drug conjugates and theranostic imaging agents towards tumor-targeted chemotherapy

open access: yes, 2014
Part I. Design, synthesis and biological evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents Filamenting temperature-sensitive protein Z (FtsZ), an essential cell division protein, is a promising target for the
Park, Bora
core  

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