Results 141 to 150 of about 2,026,427 (351)

Influence of empirically derived filtering parameters, amplicon sequence variant, and operational taxonomic unit pipelines on assessing rumen microbial diversity [PDF]

Wesley A. Tom, J.V. Judy, P.J. Kononoff, Samodha C. Fernando   +3 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Data_Sheet_5_First Comparative Analysis of Clostridium septicum Genomes Provides Insights Into the Taxonomy, Species Genetic Diversity, and Virulence Related to Gas Gangrene.PDF

, 2021
Prasad Thomas (4953331), Mostafa Y. Abdel-Glil (9108068), Anbazhagan Subbaiyan (11816387), Anne Busch (4953328), Inga Eichhorn (5830094), Lothar H. Wieler (8054873), Heinrich Neubauer (17983), Mathias Pletz (605346), Christian Seyboldt (4885246)   +8 more
openalex   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Soil bacterial taxonomic diversity is critical to maintaining the plant productivity.

Environment International, 2020
Qing‐Lin Chen, Jing Ding, Yong-guan Zhu, Ji‐Zheng He, Hangwei Hu   +4 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Multifaceted patterns of diversity and co-occurrence along an extensive survey of shrubland communities across China

Ecological Indicators
Interpreting biodiversity patterns and the underlying processes is crucial for evaluating the mechanisms of community assembly, but the view of multifaceted diversity patterns spanning broad spatial extents is less strengthened.
Dongdong Chen, Li Li, Jonathan M. Chase, Jun Hu, Huajun Yin, Chunzhang Zhao, Guozhen Shen, Chengyang Zheng, Ting Li, Xinying Cheng, Wenhong Ma, Weihua Guo, Feng Zhang, GuoYing Zhou, Lin Zhang, Anwar Mohammat, Yunxiang Li, Gaoming Xiong, Xiao Liu, Hede Gong, Fangqing Chen, Yuelin Li, Yaozhan Xu, Xiaocheng Yang, Xinrong Liao, Xin Huang, Qiurong Liu, Yao Luo, Qing Liu   +28 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

How Do the Functional Resemblance Structure and Its Component‐Dependence Change Among the Successional Stages in Degraded Karst Forests?

Ecology and Evolution
The functional resemblance structure, which mainly involved the taxonomic and functional β‐diversity, plays a key role in understanding the assembly process during succession in heterogeneous ecosystems.
Rui Yang, Qianfei Zhang, Lipeng Zang, Guangqi Zhang, Qingfu Liu, Danmei Chen, Mingzhen Sui   +6 more
doaj   +1 more source

New insights into the genetic diversity of the stone crayfish: taxonomic and conservation implications [PDF]

, 2020
Leona Lovrenčić, Lena Bonassin, Ljudevit Luka Boštjančić, Martina Podnar, Mišel Jelić, Göran Klobučar, Martina Jaklič, Valentina Slavevska-Stamenković, Jelena Hinić, Ivana Maguire   +9 more
openalex   +1 more source