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Molecular, structural, and phylogenetic analyses of Taxus chinensis JAZs

Gene, 2017
Taxus spp. are ancient gymnosperms that produce a unique secondary metabolite, namely, taxol, an anticancer drug. JAZ proteins are key regulators of the JA signaling pathway, which control taxol biosynthesis. However, the JAZ proteins of Taxus spp. are poorly studied.
Meng, Zhang   +5 more
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Taxoids from Cell Cultures of Taxus Chinensis

Phytochemistry, 1998
Abstract A cell culture of Taxus chinensis was found to produce taxoids in 4% yield (dry weight) after stimulation with methyl jasmonate. From the culture medium and cell mass, 16 taxoids were isolated. The structures were determined by two-dimensional gradient-enhanced DQF-COSY, HMQC, HMBC, and NOESY NMR experiments.
Birgitta Menhard   +4 more
openaire   +1 more source

New Taxoids from the Seeds of Taxus chinensis

Journal of Natural Products, 1998
Two new taxoids, 2alpha-acetoxy-2',7-dideacetoxyaustrospicatine (1) and decinnamoyltaxinine E (2), have been isolated from the extracts of the seeds of the Chinese yew Taxus chinensis (Pilg.) Rehd. in addition to taxuspine Z (3), taxin B (4), taxezopidine G (5), 7, 2'-bisdeacetoxyaustropicatine (6), 5alpha-cinnamoyl-9alpha,10beta, 13alpha ...
, Chen, , Chen, , Shen
openaire   +2 more sources

Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis

Phytochemistry, 1999
The taxoid chinentaxunine has been isolated from the seeds of Chinese yew Taxus chinensis, and its structure determined on the basis of spectral and chemical methods. In addition, the known taxol C, paclitaxel, 10-deacetyl taxol A, 10-deacetyl-7-epitaxol, 10-deacetyl-10-oxo-7-epi-taxol, taxinine M, taxchinin A, 10-deacetyl taxinine B and taxuspine X ...
Y C, Shen, Y J, Chen, C Y, Chen
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A New 1,2-Deoxytaxane Diterpenoid fromTaxus chinensis

Planta Medica, 1998
The bark of Taxus chinensis yielded a new taxane diterpenoid, 2-deacetoxy-7,9-dideacetyltaxinine J ( 1) together with several known taxoids. (1)H- and (13)C-NMR data of 1 are reported.
J Y, Liang, K S, Huang, A A, Gunatilaka
openaire   +2 more sources

A new endophytic taxane production fungus from Taxus chinensis

Applied Biochemistry and Microbiology, 2009
More than 50 kinds of endophytic fungi associated with Taxus chinensis, were isolated and examined as potential source of the imposing anticancer drug taxol. Of these, 4 isolates show ability to produce taxane when measured with the competitive inhibition enzyme immunoassay method.
Z, Miao, Y, Wang, X, Yu, B, Guo, K, Tang
openaire   +2 more sources

Multidrug Resistant Cancer Cells Susceptibility to Cytotoxic Taxane Diterpenes from Taxus yunnanensis and Taxus chinensis

Bioorganic & Medicinal Chemistry Letters, 2002
Twelve taxane diterpenes (1-12), which were isolated previously from the EtOH extract of the aerial parts of Taxus yunnanensis or Taxus chinensis, were evaluated for cytotoxicity against the multidrug resistant cancer cells KB-VIN and KB-7d. Compounds and showed significant cytotoxicity in these cell lines.
Youichi, Shinozaki   +6 more
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Chemistry of Chinese yew, Taxus chinensis var. mairei

Biochemical Systematics and Ecology, 2008
Abstract Taxus chinensis var. mairei (Lemee et Levl) Cheng et L.K. Fu is an evergreen tall tree ubiquitous to the southeastern region in China. The first chemical study on this species was published in 1987. Since then about 163 compounds including taxoids and non-taxane compounds were isolated from seeds, root, bark and leaves of this species ...
Cunfang Li   +3 more
openaire   +1 more source

Two New Taxoids fromTaxus chinensis

Chemistry & Biodiversity, 2005
Two new taxoids, 2,20-O-diacetyltaxumairol N (1) and 14beta-hydroxy-10-deacetyl-2-O-debenzoylbacatin III (2), were isolated from the needles and stems of Taxus chinensis. Their structures were determined on the basis of extensive 1D- and 2D-NMR-spectral analysis.
Zhi-Hua, Xia   +5 more
openaire   +2 more sources

Cryopreservation of Taxus chinensis suspension cell cultures.

Cryo letters, 2002
A simple cryopreservation method for suspension cells of Taxus chinensis was established. In this procedure 7 days old suspension cells were used without any pre-culture treatment. At first, cells were incubated in cryoprotectant solution (0.5M DMSO and 0.5M glycerol) on ice for 30 min and then frozen at a cooling rate of 1 degree C/min to -40 degrees ...
S I, Kim   +9 more
openaire   +1 more source

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