Results 151 to 160 of about 1,823 (182)

A new endophytic taxane production fungus from Taxus chinensis

Applied Biochemistry and Microbiology, 2009
More than 50 kinds of endophytic fungi associated with Taxus chinensis, were isolated and examined as potential source of the imposing anticancer drug taxol. Of these, 4 isolates show ability to produce taxane when measured with the competitive inhibition enzyme immunoassay method.
Z, Miao, Y, Wang, X, Yu, B, Guo, K, Tang
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New Taxoids from the Seeds of Taxus chinensis

Journal of Natural Products, 1998
Two new taxoids, 2alpha-acetoxy-2',7-dideacetoxyaustrospicatine (1) and decinnamoyltaxinine E (2), have been isolated from the extracts of the seeds of the Chinese yew Taxus chinensis (Pilg.) Rehd. in addition to taxuspine Z (3), taxin B (4), taxezopidine G (5), 7, 2'-bisdeacetoxyaustropicatine (6), 5alpha-cinnamoyl-9alpha,10beta, 13alpha ...
, Chen, , Chen, , Shen
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Multidrug Resistant Cancer Cells Susceptibility to Cytotoxic Taxane Diterpenes from Taxus yunnanensis and Taxus chinensis

Bioorganic & Medicinal Chemistry Letters, 2002
Twelve taxane diterpenes (1-12), which were isolated previously from the EtOH extract of the aerial parts of Taxus yunnanensis or Taxus chinensis, were evaluated for cytotoxicity against the multidrug resistant cancer cells KB-VIN and KB-7d. Compounds and showed significant cytotoxicity in these cell lines.
Youichi, Shinozaki, Narihiko, Fukamiya, Chieko, Uchiyama, Masayoshi, Okano, Kiyoshi, Tagahara, Kenneth F, Bastow, Kuo-Hsiung, Lee   +6 more
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Chemistry of Chinese yew, Taxus chinensis var. mairei

Biochemical Systematics and Ecology, 2008
Abstract Taxus chinensis var. mairei (Lemee et Levl) Cheng et L.K. Fu is an evergreen tall tree ubiquitous to the southeastern region in China. The first chemical study on this species was published in 1987. Since then about 163 compounds including taxoids and non-taxane compounds were isolated from seeds, root, bark and leaves of this species ...
Cunfang Li, Changhong Huo, Manli Zhang, Qingwen Shi   +3 more
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Two New Taxoids fromTaxus chinensis

Chemistry & Biodiversity, 2005
Two new taxoids, 2,20-O-diacetyltaxumairol N (1) and 14beta-hydroxy-10-deacetyl-2-O-debenzoylbacatin III (2), were isolated from the needles and stems of Taxus chinensis. Their structures were determined on the basis of extensive 1D- and 2D-NMR-spectral analysis.
Zhi-Hua, Xia, Li-Yan, Peng, Yu, Zhao, Gang, Xu, Qin-Shi, Zhao, Han-Dong, Sun   +5 more
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Cryopreservation of Taxus chinensis suspension cell cultures.

Cryo letters, 2002
A simple cryopreservation method for suspension cells of Taxus chinensis was established. In this procedure 7 days old suspension cells were used without any pre-culture treatment. At first, cells were incubated in cryoprotectant solution (0.5M DMSO and 0.5M glycerol) on ice for 30 min and then frozen at a cooling rate of 1 degree C/min to -40 degrees ...
S I, Kim, H K, Choi, J S, Son, J H, Yun, M S, Jang, H R, Kim, J Y, Song, J H, Kim, H J, Choi, S S, Hong   +9 more
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Determination of taxol in Taxus chinensis by HPLC method.

Yao xue xue bao = Acta pharmaceutica Sinica, 1992
A method for the determination of taxol in Taxus chinensis by HPLC method using betamethasone as internal standard is described. The column employed was packed with 10 microns silica gel YWG 80 (250 x 4 mm), the eluting solvent consisted of CH2Cl2--MeOH (95:5) and the effluent was monitored at 228 nm. The coefficients of variation are less than 2%.
L X, Xu, A R, Liu
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Enhancement of paclitaxel production by temperature shift in suspension culture of Taxus chinensis

Enzyme and Microbial Technology, 2000
Effect of temperature shift during culture period on cell growth and paclitaxel was investigated to optimize paclitaxel production in suspension culture of Taxus chinensis. Cell growth showed the optimum at 24 degrees C while paclitaxel synthesis showed the maximum at 29 degrees C. To minimize the inhibitory effect of higher temperature on cell growth,
, Choi, , Kim, , Son, , Hong, , Lee, , Lee   +5 more
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[Chemical constituents of Taxus chinensis var. mairei cell cultures].

Yao xue xue bao = Acta pharmaceutica Sinica, 2015
The chemical constituents of Taxus chinensis var. mairei cell cultures were investigated by chromatographic methods, including silica gel column chromatography, Sephadex LH-20 and preparative HPLC. Thirteen compounds were isolated from the 80% ethanol extract of cultured cells and their structures were elucidated by spectral data and physicochemical ...
Xiang-yang, Bai, Jian-ming, Lü, Yan-ying, Zhou, Zi-rong, Zhu, Ren-wang, Jiang, Wei, Zhang   +5 more
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Two New Taxoids from the Needles and Stems of Taxus chinensis

HETEROCYCLES, 2005
Two new taxoids, named 10-O-benzoyl-15-O-acetyltaxumairol X (1) and 5-O-acetyl-20-O-deacetyl-4,20-p-hydroxylbenzylidenedioxytaxuyunnanine L (2), were isolated from the needles and stems of Taxus chinensis. Their structures were determined on the basis of combined 1D and 2D spectral techniques.
Qin-Shi Zhao, Zhi-Hua Xia, Li-Yan Peng, Rong-Tao Li, Han-Dong Sun   +4 more
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