Results 61 to 70 of about 76,145 (237)

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Health‐Related Quality of Life in Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis: A Qualitative Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Epidermal necrolysis (EN), including Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe cutaneous drug reactions with high morbidity. However, the quality of life (QoL) impact during acute hospitalization is not well understood.
Jacob McFeeters, Allison Yan, Cole Veliky, Matthew Gallardo, Kelsey Nusbaum, Rachel Kirven, Kristopher Fisher, Abraham Korman, Hyoshin Kim, Benjamin H. Kaffenberger   +9 more
wiley   +1 more source

Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats

Asian Journal of Pharmaceutical Sciences, 2019
To assess the mechanism of the pharmacokinetic interaction between piperacillin and tazobactam, renal excretion and pharmacokinetic studies of piperacillin/tazobactam were investigated in normal and bacteremia rats.
Shilei Yang, Zhihao Liu, Changyuan Wang, Shijie Wen, Qiang Meng, Xiaokui Huo, Huijun Sun, Xiaodong Ma, Jinyong Peng, Zhonggui He, Kexin Liu   +10 more
doaj   +1 more source

Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]

, 2017
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core   +1 more source

Anterolateral‐Thigh Fascia Lata Free Flap Versus Fibula Free Flap for Mandibular Osteoradionecrosis

The Laryngoscope, EarlyView.
The anterolateral thigh fascia lata “rescue” free flap has been employed as a novel tool in the treatment of advanced partial thickness mandibular osteoradionecrosis. Compared with the traditional fibula free flap for the same indication, the “rescue” flap provides similar outcomes in terms of disease resolution, superior functional outcomes, and ...
Conrad K. Blunck, Alexander Havens, Michael A. Fritz, Brandon L. Prendes, Derek J. Vos, Amani Alvi, Sara Liu, Dane J. Genther, Peter J. Ciolek   +8 more
wiley   +1 more source

Piperacillin/Tazobactam Co-Delivery by Micellar Ionic Conjugate Systems Carrying Pharmaceutical Anions and Encapsulated Drug

Pharmaceutics
Previously obtained amphiphilic graft copolymers based on [2-(methacryloyloxy)ethyl]trimethylammonium chloride (TMAMA) ionic liquid were used as the matrices of three types of nanocarriers, i.e., conjugates with ionic piperacillin (PIP) and micelles with
Katarzyna Niesyto, Aleksy Mazur, Dorota Neugebauer   +2 more
doaj   +1 more source

Cost-effectiveness of ceftolozane/tazobactam compared with piperacillin/tazobactam as empiric therapy based on the in-vitro surveillance of bacterial isolates in the United States for the treatment of complicated urinary tract infections

BMC Infectious Diseases, 2017
Background A challenge in the empiric treatment of complicated urinary tract infection (cUTI) is identifying the initial appropriate antibiotic therapy (IAAT), which is associated with reduced length of stay and mortality compared with initial ...
Teresa L Kauf, Vimalanand S. Prabhu, Goran Medic, Rebekah H. Borse, Benjamin Miller, Jennifer Gaultney, Shuvayu S. Sen, Anirban Basu   +7 more
doaj   +1 more source

Hepatic portal venous gas : comparison of two cases [PDF]

, 2013
Peer reviewedPublisher ...
Rankin, Iain, Sheth, Hemant
core   +3 more sources

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, EarlyView.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source

Results of the effectiveness of two piperacillin–tazobactam molecules in the real world

International Journal of Infectious Diseases, 2018
Objective: The objective was to determine the effectiveness of two piperacillin–tazobactam molecules in terms of all-cause mortality, mortality by infection, and hospital stay.
Jorge Enrique Machado-Alba, Andres Gaviria-Mendoza, Manuel E. Machado-Duque   +2 more
doaj   +1 more source