Results 91 to 100 of about 44,793 (291)

A regulated two-step mechanism of TBP binding to DNA: A solvent-exposed surface of TBP inhibits TATA box recognition

open access: yes, 2002
The TATA box binding protein TBP plays a universally important role in eukaryotic nuclear transcription. By mutagenesis, we have discovered a solvent-exposed surface of the structured TBP core domain that is important for inhibition of the DNA binding ...
Herr, Winship   +3 more
core   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

open access: yesChemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal   +3 more
wiley   +1 more source

TBP-like Factors Come into Focus [PDF]

open access: yesCell, 2000
The papers by Dantonel et al. 2000xDantonel, J.-C, Quintin, S, Lakatos, L, Labouesse, M, and Tora, L. Mol. Cell. 2000; 6: 715–722Abstract | Full Text | Full Text PDF | PubMedSee all ReferencesDantonel et al. 2000 and Kaltenbach et al. 2000xKaltenbach, L, Horner, M.A, Rothman, J.H, and Mango, S.E. Mol. Cell.
openaire   +2 more sources

TBP genomic profiles.

open access: yes, 2016
TBP amplification pattern of the 37 grapevine accessions of Table 1. Cvs are ordered according to cluster analysis of Fig 2. Blue boxes indicate few polymorphisms associated to clones of the same cv. (NBC vs NBR and MEM vs MR5).
Francesco Mastromauro (3126999)   +5 more
core   +1 more source

Extracellularly Activatable Conjugates of RGD Peptidomimetics and Cryptophycin for αVβ3‐Targeted Cancer Therapy

open access: yesChemistry – A European Journal, EarlyView.
Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt   +3 more
wiley   +1 more source

MEASUREMENT OF THE VAPOR PRESSURE OF TBP

open access: yes, 1961
Two methods, the transpiration and direct P/sup 32/ counting methods, were tested for use in measuring the vapor pressure of TBP. With the transpiration technique, measured TBP vapor pressures were sufficiently reproducible, and probably of sufficient ...
Faure, A., Davis, W. Jr.
core   +1 more source

Data‐driven simulation of crude distillation using Aspen HYSYS and comparative machine learning models

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Integrated Aspen HYSYS–machine learning framework for predicting product yields and quality variables. Abstract Crude oil refining is a complex process requiring precise modelling to optimize yield, quality, and efficiency. This study integrates Aspen HYSYS® simulations with machine learning techniques to develop predictive models for key refinery ...
Aldimiro Paixão Domingos   +3 more
wiley   +1 more source

Xylose Acetals ‐ a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova   +8 more
wiley   +1 more source

Raman Spectroscopic Study on Extraction of U(Ⅵ) From HNO3-HClO4 Solutions by Tributyl Phosphate

open access: yesHe huaxue yu fangshe huaxue
99Tc is a major radioactive fission product of 235U and 239Pu during the operation of nuclear reactors, and with a half-life time of 2.11×105 years it is also a long-term contributor to radiotoxicity of spent nuclear fuel.
Hong-ming ZHANG   +6 more
doaj   +1 more source

PolyQ dependence of relative nuclear and cytoplasmic TBP protein levels

open access: yes, 2011
Copyright information:Taken from "HAP1 can sequester a subset of TBP in cytoplasmic inclusions via specific interaction with the conserved TBP"http://www.biomedcentral.com/1471-2199/8/76BMC Molecular Biology 2007;8():76-76.Published online 14 Sep ...
Justin R Prigge (36725)   +1 more
core   +1 more source

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