Distinct Roles for TBP and TBP-Like Factor in Early Embryonic Gene Transcription in Xenopus [PDF]
Science, 2000 The TATA-binding protein (TBP) is believed to function as a key component of the general transcription machinery. We tested the role of TBP during the onset of embryonic transcription by antisense oligonucleotide–mediated turnover of maternal TBP messenger RNA.
Weeks, D.L. +2 more
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Identification of a mouse TBP-like protein (TLP) distantly related to the Drosophila TBP-related factor [PDF]
Nucleic Acids Research, 1999 TATA-binding protein (TBP) is an essential factor for eukaryotic transcription. In this study, we demonstrated a mouse cDNA encoding a 21 kDa TBP-like protein (TLP). The TLP ORF, carrying 186 amino acids, covered the entire 180 amino acids of the C-terminal conserved domain of mouse TBP with 39% identity and 76% similarity.
T, Ohbayashi, Y, Makino, T A, Tamura
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A kinetic model of TBP auto-regulation exhibits bistability [PDF]
Biology Direct, 2010 Background TATA Binding Protein (TBP) is required for transcription initiation by all three eukaryotic RNA polymerases. It participates in transcriptional initiation at the majority of eukaryotic gene promoters, either by direct association to the TATA ...
Gokhale Sucheta A +4 more
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Structure of a mammalian TBP (TATA-binding protein) gene: isolation of the mouse TBP genome
Nucleic Acids Research, 1993 TBP is a general transcription factor required for all classes of eukaryotic genes. C-terminal 180 amino acid residues which are necessary for basal transcription were highly conserved among species, whereas N-terminal residues of TBP are diverse (1-7 ...
K, Sumita +6 more
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Role of high mobility group box 1 (HMGB1) in SCA17 pathogenesis. [PDF]
PLoS ONE, 2014 Spinocerebellar ataxia type 17 (SCA17) involves the expression of a polyglutamine (polyQ) expanded TATA-binding protein (TBP), a general transcription initiation factor. TBP interacts with other protein factors, including high mobility group box 1 (HMGB1)
Li-Ching Lee +5 more
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Analysis of a hybrid TATA box binding protein originating from mesophilic and thermophilic donor organisms [PDF]
, 2010 The TATA Box Binding Protein (TBP) is a 20 kD protein that is essential and universally conserved in eucarya and archaea. Especially among archaea, organisms can be found that live below 0°C as well as organisms that grow above 100°C.
Soppa, Jörg +2 more
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Cell Communication and Signaling, 2023 Background Skeletal muscle is comprised of heterogeneous myofibers that differ in their physiological and metabolic parameters. Of these, slow-twitch (type I; oxidative) myofibers have more myoglobin, more mitochondria, and higher activity of oxidative ...
Manting Ma +7 more
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A Conserved GA Element in TATA-Less RNA Polymerase II Promoters [PDF]
, 2011 Initiation of RNA polymerase (Pol) II transcription requires assembly of the pre-initiation complex (PIC) at the promoter. In the classical view, PIC assembly starts with binding of the TATA box-binding protein (TBP) to the TATA box.
Hartmann, H. +32 more
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Diagnostic Accuracy of Pleural Effusion Mononuclear Cells/Leukocyte Ratio in Tuberculous Pleurisy
Frontiers in Medicine, 2021 Background: Tuberculous pleurisy (TBP) is a common clinical type of tuberculosis (TB) in China. TBP is difficult to diagnose. Whether the mononuclear cell/leukocyte (MNC/LEU) ratio in pleural effusion can contribute to accurate TBP diagnosis remains yet ...
Xiaoli Lei, Junli Wang, Zhigang Yang
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Extracción de cromo con disolventes orgánicos. II parte. Extracción con TBP y con Primene 81R
Revista de Metalurgia, 1998 Se estudia el empleo de un reactivo de carácter neutro (TBP) y otro de carácter básico (Primene 81R) para llevar a cabo la extracción del cromo presente en disoluciones acuosas.
D. de Juan, V. Meseguer, L. J. Lozano
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