Results 11 to 20 of about 44,938 (289)
Structures and implications of TBP–nucleosome complexes [PDF]
Proceedings of the National Academy of Sciences, 2021 Significance The TATA box-binding protein (TBP) is highly conserved throughout eukaryotes and plays a central role in the assembly of the transcription preinitiation complex (PIC) at the promoter of genes. We show here that TBP can interact with nucleosomes containing the Widom-601 sequence at two different positions.
Wang, Haibo, Xiong, Le, Cramer, Patrick
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Selective Use of TBP and TFIIB Revealed by a TATA-TBP-TFIIB Array with Altered Specificity [PDF]
Science, 1997 Interaction between the TATA box-binding protein TBP and TFIIB is critical for transcription in vitro. An altered-specificity TBP-TFIIB interaction was rationally designed and linked in sequence to an altered-specificity TATA box-TBP interaction to study how TBP and TFIIB function together to support transcription in human cells.
W P, Tansey, W, Herr
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Distinct Roles for TBP and TBP-Like Factor in Early Embryonic Gene Transcription in Xenopus [PDF]
Science, 2000 The TATA-binding protein (TBP) is believed to function as a key component of the general transcription machinery. We tested the role of TBP during the onset of embryonic transcription by antisense oligonucleotide–mediated turnover of maternal TBP messenger RNA.
Weeks, D.L. +2 more
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Structure of a mammalian TBP (TATA-binding protein) gene: isolation of the mouse TBP genome [PDF]
Nucleic Acids Research, 1993 TBP is a general transcription factor required for all classes of eukaryotic genes. C-terminal 180 amino acid residues which are necessary for basal transcription were highly conserved among species, whereas N-terminal residues of TBP are diverse (1-7 ...
K, Sumita +6 more
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Identification of a mouse TBP-like protein (TLP) distantly related to the Drosophila TBP-related factor [PDF]
Nucleic Acids Research, 1999 TATA-binding protein (TBP) is an essential factor for eukaryotic transcription. In this study, we demonstrated a mouse cDNA encoding a 21 kDa TBP-like protein (TLP). The TLP ORF, carrying 186 amino acids, covered the entire 180 amino acids of the C-terminal conserved domain of mouse TBP with 39% identity and 76% similarity.
T, Ohbayashi, Y, Makino, T A, Tamura
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TBP, un facteur de transcription universel ? [TBP, a universal transcription factor ?] [PDF]
, 2004 The TATA binding protein (TBP) is a subunit of several macromolecular complexes required for transcription by the three nuclear RNA polymerases. This observation led to the idea that TBP is a "universal" transcription factor. The discovery of three TBP-related factors and a macromolecular complex which lacks TBP but can support RNA polymerase II ...
Davidson, Irwin +2 more
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A kinetic model of TBP auto-regulation exhibits bistability [PDF]
Biology Direct, 2010 Background TATA Binding Protein (TBP) is required for transcription initiation by all three eukaryotic RNA polymerases. It participates in transcriptional initiation at the majority of eukaryotic gene promoters, either by direct association to the TATA ...
Gokhale Sucheta A +4 more
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TBP Dynamics in Living Human Cells: Constitutive Association of TBP with Mitotic Chromosomes [PDF]
Molecular Biology of the Cell, 2002 The recruitment of TATA binding protein (TBP) to gene promoters is a critical rate-limiting step in transcriptional regulation for all three eukaryotic RNA polymerases. However, little is known regarding the dynamics of TBP in live mammalian cells. In this report, we examined the distribution and dynamic behavior of green fluorescence protein (GFP ...
Danyang, Chen +3 more
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The TATA‐Box‐Binding Protein (TBP) of Halobacterium Salinarum [PDF]
European Journal of Biochemistry, 1997 The TATA‐box binding protein (TBP) is a basal transcription factor involved in transcription initiation in Eucarya and Archaea. Using a tbp‐specific probe, a 4.5‐kbp genomic fragment from Halobacterium salinarum was cloned and sequenced. It contained the tbp gene and the 5’‐ends of two additional open reading frames, but surprisingly, 70% of the cloned
J, Soppa, T A, Link
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Analysis of a hybrid TATA box binding protein originating from mesophilic and thermophilic donor organisms [PDF]
, 2010 The TATA Box Binding Protein (TBP) is a 20 kD protein that is essential and universally conserved in eucarya and archaea. Especially among archaea, organisms can be found that live below 0°C as well as organisms that grow above 100°C.
Soppa, Jörg +2 more
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