Results 131 to 140 of about 10,615 (216)

Real‐World Effectiveness and Safety of Tirzepatide in Type 1 Diabetes and Obesity: Impact on Glycaemia, Weight, and Cardiometabolic Risk Markers

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8836-8846, October 2026.
ABSTRACT Aims To evaluate the effectiveness and safety of tirzepatide on glycaemia, weight, and markers of cardiometabolic risk in people with type 1 diabetes and obesity. Materials and Methods This retrospective cohort study compared 142 adults with type 1 diabetes (BMI ≥ 30 kg/m2) initiated on tirzepatide against 50 age‐, sex‐ and BMI‐matched ...
Simon A. Berry   +4 more
wiley   +1 more source

Real‐World Effectiveness and Safety of a Tubeless Automated Insulin Delivery System With an Adaptive Control Algorithm (APGO) in Children and Adolescents With Type 1 Diabetes: A Multicentre Observational Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9275-9283, October 2026.
ABSTRACT Aim Automated insulin delivery (AID) systems improve glycaemic outcomes in Type 1 diabetes; however, paediatric real‐world data on newly introduced tubeless AID systems remain limited. We aimed to provide the first clinical evaluation of the A8 TouchCare Nano AID system with the APGO algorithm in children and adolescents with Type 1 diabetes ...
Angela Zanfardino   +9 more
wiley   +1 more source

Comparison of Diluted Insulin (U10) Versus Standard (U100) Insulin in Automated Insulin Delivery Systems: Reducing Time Below Range in Young Children

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8966-8973, October 2026.
ABSTRACT Background Treating young children with Type 1 diabetes (CwT1D) is challenging due to their very small need for insulin. We investigated the safety of diluted insulin (U10) in the AID system and how its use affected glycaemic outcomes compared to standard insulin.
Heidi Falk   +4 more
wiley   +1 more source

Association of Variability of Monthly Continuous Glucose Monitoring‐Derived Metrics With Diabetic Kidney Disease in Type 1 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9044-9053, October 2026.
ABSTRACT Background While HbA1c is the standard for monitoring long‐term glycaemic control, it fails to capture glycaemic variability. We investigated the discriminatory capacity of longitudinal continuous glucose monitoring (CGM) metrics and identified CGM metric patterns associated with diabetic kidney disease (DKD) in individuals with type 1 ...
Byeongjae Kang   +8 more
wiley   +1 more source

Looking Beyond Glycaemic Control: Real‐World 12‐Month Cardiometabolic and Retinopathy Outcomes Following Omnipod 5 Initiation in People With Type 1 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9166-9177, October 2026.
ABSTRACT Aims To evaluate the real‐world effectiveness, safety, and tolerability of the Omnipod 5 hybrid closed‐loop system in adults with type 1 diabetes (T1D) with a novel focus on cardiometabolic markers alongside diabetic eye disease and renal function. Methods A single‐centre, retrospective analysis of adults with T1D using Omnipod 5 was conducted.
Eleanor McNally   +8 more
wiley   +1 more source

Postprandial Glycemic Control With Automated Insulin Delivery With Control‐IQ Technology: The Impact of Meal Composition

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9178-9187, October 2026.
ABSTRACT Aims To evaluate the efficiency of the AID system with Control‐IQ technology and carbohydrate counting (CHC)–based premeal bolus to control postprandial glucose (PPG) after mixed meals with different macronutrient compositions in adolescents with type 1 diabetes (T1D).
Marco Marigliano   +8 more
wiley   +1 more source

Association Between Time in Range and Advanced Cardiovascular‐Kidney‐Metabolic Syndrome in Older Adults With Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9265-9274, October 2026.
ABSTRACT Aims Cardiovascular, kidney and metabolic diseases are pathophysiologically interrelated and are conceptualised within the cardiovascular‐kidney‐metabolic (CKM) syndrome framework. However, evidence linking continuous glucose monitoring (CGM) to CKM syndrome remains limited.
Hang Su   +7 more
wiley   +1 more source

Principal component analysis of Tbr transcriptomes comparing human isolates from Nkhotakota (16 isolates), Rumphi (Eight isolates), Uganda (Four isolates) and Tbr isolates passaged in rodents.

open access: yes
Principal component analysis of Tbr transcriptomes comparing human isolates from Nkhotakota (16 isolates), Rumphi (Eight isolates), Uganda (Four isolates) and Tbr isolates passaged in rodents.
Oscar Nyangiri (11134007)   +9 more
core   +1 more source

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