A dataset on the multi-species and multi-endpoint bioanalytical assessment of environmental samples derived from Swedish wastewater treatment plants. [PDF]
Data BriefLungu-Mitea S +7 more
europepmc +1 more source
Cell type- and species-specific regulation of hepatic lncRNAs by TCDD-activated aryl hydrocarbon receptor. [PDF]
Sci RepPost GA +3 more
europepmc +1 more source
Beneficial and detrimental consequences of AHR activation in intestinal infection. [PDF]
Life Sci AllianceDiaz OE +6 more
europepmc +1 more source
Lancet, The, 2009 BACKGROUND: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has a long half-life of 5-10 years in human beings as a result of its high lipophilicity, and little or no metabolism.
Olivier Sorg
exaly +2 more sources
Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on Hormones of Energy Balance in a TCDD-Sensitive and a TCDD-Resistant Rat Strain [PDF]
International Journal of Molecular Sciences, 2014 One of the hallmarks of the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a drastically reduced feed intake by an unknown mechanism. To further elucidate this wasting syndrome, we followed the effects of a single large dose (100 μg/kg) of TCDD on the serum levels of several energy balance-influencing hormones, clinical chemistry ...
Sanna Lensu +2 more
exaly +9 more sources
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To investigate the relationship between vitamin A status and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) lethality, the influence of TCDD on tissue and serum vitamin A levels was determined in the most TCDD-susceptible (Long-Evans) and the most TCDD-resistant (Han/Wistar) rat strains.
Helen Håkansson +1 more
exaly +3 more sources
Fate and transport of 1278-TCDD, 1378-TCDD, and 1478-TCDD in soil–water systems
Science of The Total Environment, 2006The most toxic dioxin is 2,3,7,8-tetrachlorodibenzo-p-dioxin (2378-TCDD), and obtaining comprehensive experimental data for this compound is challenging. However, several nontoxic isomers of 2378-TCDD exist, and can provide significant experimental evidence about this highly toxic dioxin.
Zhaosheng, Fan +3 more
openaire +2 more sources
Secretion of TCDD in milk and cream following the feeding of TCDD to lactating dairy cows
Bulletin of Environmental Contamination and Toxicology, 1982This study has shown that the level of TCDD secreted into milk and cream are such as to suggest that the residue found is proportional to the TCDD diet level and to the fat content of the milk or cream. After TCDD is removed from the diet the amount of TCDD secreted into milk decreases with time having a half-life of 41 days.
R A Hummel
exaly +3 more sources
Influence of phenobarbital and TCDD on the hepatic metabolism of TCDD in the dog
Experientia, 1985The influence of phenobarbital and TCDD pretreatment on the formation and biliary excretion of TCDD-metabolites following single doses of 3H-TCDD was investigated. Without pretreatment, 24.5% of the absorbed 3H-TCDD dose was excreted in the bile within 110 h. Phenobarbital did not influence this rate, whereas a single dose of 10 micrograms of unlabeled
H, Poiger, C, Schlatter
openaire +2 more sources
Abstract Two rat strains differ widely (over 300-fold) in their LD50-values for TCDD. We have compared the effects of TCDD on brain aminergic systems in the two rat strains to assess the role of these systems in the strain difference. Rats of both strains were given 50 μg/kg TCDD (LD100 for Long-Evans [L-E] rats; nonlethal to Han/Wistar [H/W] rats ...
M. Unkila +3 more
openaire +3 more sources