Results 161 to 170 of about 13,392 (209)

A microbial metabolite of TCDD

Experientia, 1982
In the present study we describe the occurrence of a metabolite of TCDD, which arose in several microbial cultures after long term incubation. The polar metabolite amounted approximately 1% of the input material, and was found to be a hydroxylated derivative of TCDD.
M, Philippi, J, Schmid, H K, Wipf, R, Hütter   +3 more
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Biological degradation of TCDD in rats

Nature, 1979
Apart from its high toxicity, the chemical stability and persistence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the environment bring about additional hazards. However, until now there has been no evidence for degradation of this dioxin in biological systems, and it is considered unusual that a compound which is insusceptible to biological attack
H, Poiger, C, Schlatter
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The epidemiology and toxicology of TCDD

Bulletin of Environmental Contamination and Toxicology, 1984
The toxicology and epidemiology of dioxin is a broad subject, so I will very briefly review the animal toxicology, then the early studies we conducted here in Missouri and finally other human aspects of TCDD exposure. Figure i is the chemical structure of 2,3,7,8 tetrachlorodibenzodioxin.
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Tissue Distribution, Metabolism, and Excretion of¹⁴C‐TCDD in a TCDD‐Susceptible and a TCDD‐Resistant Rat Strain^a

Pharmacology & Toxicology, 1990
A comparative study was carried out in the most TCDD‐resistant [Han/Wistar (H/W), LD50 > 3000 μg/kg] and the most TCDD‐susceptible [Long‐Evans (L‐E), LD50 about 10 μg/kg] rat strain to assess the significance of kinetic factors in TCDD toxicity. Young adult males of both strains were administered 5 μg/kg (1.9 μCi/kg)14C‐TCDD intraperitoneally.
R, Pohjanvirta, T, Vartiainen, A, Uusi-Rauva, J, Mönkkönen, J, Tuomisto   +4 more
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TCDD Contamination in the Seveso Incident

Drug Metabolism Reviews, 1982
(1982). TCDD Contamination in the Seveso Incident. Drug Metabolism Reviews: Vol. 13, No. 3, pp. 407-422.
R, Fanelli, C, Chiabrando, A, Bonaccorsi
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Teratogenic potency of TCDD, TCDF and TCDD-TCDF combinations in C57BL/6N mice

Toxicology Letters, 1985
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 2,3,7,8-tetrachlorodibenzofuran (TCDF) cause the same spectrum of fetal anomalies in C57BL/6N mice. Pregnant dams were treated with TCDD, TCDF and combinations of the 2 compounds on gestation day 10, and examined for maternal and fetal effects on day 18. The fetal kidneys were the most sensitive target for
H, Weber, M W, Harris, J K, Haseman, L S, Birnbaum   +3 more
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Epidemiological Problems with TCDD (A Critical View)

Drug Metabolism Reviews, 1982
(1982). Epidemiological Problems with TCDD (A Critical View) Drug Metabolism Reviews: Vol. 13, No. 3, pp. 447-469.
G, Tognoni, A, Bonaccorsi
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Environmental Toxicity of TCDD

1983
Data on toxicity of TCDD to organisms, concentrations in the organisms, and concentrations in the media in and on which the organisms live can help determine the importance of measured levels of TCDD in the environment as part of the hazard assessment process.
E. E. Kenaga, L. A. Norris
openaire   +1 more source

[Neuropsychopharmacological effects of TCDD].

Bollettino della Societa italiana di biologia sperimentale, 1979
It has been found that TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin), in rats, endoperitoneally or orally administered at dose of 1-10 mcg/kg, provokes irritability, aggressivity and restlessness (increase of spontaneous crossings in the shuttle box). The TCDD does not modify the conditioned avoidance (C.A.) or the conflictual situation.
E, Creso, V, De Marino, L, Donatelli, G, Pagnini   +3 more
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Dechlorinating TCDD

Environmental Science & Technology, 1995
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