Results 71 to 80 of about 22,324 (258)

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Schwannome bénin primitif de la plèvre

The Pan African Medical Journal, 2019
Le schwannome est une tumeur neurogène développée à partir des cellules de Schwann. Dans la région thoracique, le médiastin est le principal site d'apparition du schwannome.
Rachid Marouf, Ihsan Alloubi
doaj   +1 more source

A Novel Bipolar DC Connection Strategy for Photovoltaic Power Plants With a 50% Reduction in DC Cabling Length

Energy Science &Engineering, EarlyView.
Bipolar configuration is a new topology in the direct current (DC) system of photovoltaic power plants, which is topologically analogous to the bipolar configuration utilised in High‐Voltage Direct Current power transmission systems. DC cable length and copper usage are reduced by 50% using a bipolar configuration.
Duško M. Tovilović, Željko R. Đurišić, Vladan R. Durković   +2 more
wiley   +1 more source

Reevaluating the rule of two's: Age and epidemiological variations in Meckel's diverticulum

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective To evaluate the clinical characteristics, diagnostic modalities, and age‐related variation of Meckel's diverticulum (MD) using data from a nationwide pediatric inpatient database and a single‐center institutional cohort. Methods The Kids' Inpatient Database (KID) for 2016 and 2019 was queried for patients with a principal diagnosis ...
Ashley Polachek, Megha S. Mehta, Ahmed Shalaby, Aamirah Vadsariya, Wenjing Zong, David M. Troendle   +5 more
wiley   +1 more source

The impact of a vancomycin intervention on vancomycin‐associated nephrotoxicity in children: a quality improvement initiative

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Vancomycin is first‐line treatment for methicillin‐resistant Staphylococcus aureus (MRSA) infections. However, despite guideline recommendations, there is no evidence that targeting vancomycin trough concentrations of ≥15 mg/L in children confers clinical benefit and is associated with vancomycin‐associated nephrotoxicity (VAN ...
Megan R. Nettleton, Hwi‐Eun Mary Shim, Joanne Abbotsford, Zoy Goff, Briony Hazelton, Matthew O'Brien, Tenielle Porter, Thomas Snelling, Daniel K. Yeoh, Asha C. Bowen, Christopher C. Blyth, Anita J. Campbell   +11 more
wiley   +1 more source

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience

JPGN Reports, EarlyView.
Abstract Objectives To evaluate the durability and predictors of loss of response of infliximab (IFX) over 2 years in paediatric Crohn's disease (CD) utilizing a proactive therapeutic drug monitoring (TDM) strategy. Methods A retrospective, single‐centre cohort study was conducted at The Children's Hospital at Westmead (CHW), Australia, from January ...
Cher Wei Chuah, Jessica Eldredge, Annabel Magoffin, Edward Vincent O'Loughlin, Calvin Joomann Park, Juliana Puppi, Susan Siew, Michael Stormon, Kunal Thacker, Shoma Dutt   +9 more
wiley   +1 more source

Developing text and data mining (TDM) support within a university research library

Insights: The UKSG Journal
The introduction of the text and data mining (TDM) exception in 2014 led to researchers asking for support from staff within Library Services at the University of Birmingham.
Lisa Bird, James Barnett
doaj   +1 more source

Safety Profile of Nebulized Ciprofloxacin‐Dexamethasone After Pediatric Airway Surgery

The Laryngoscope, EarlyView.
ABSTRACT Objective To evaluate the safety profile and patterns of use of nebulized ciprofloxacin–dexamethasone (CPD) in pediatric patients undergoing airway surgery. Methods A retrospective chart review was performed of patients who underwent airway surgery at a tertiary pediatric center between 2019 and 2023 and received nebulized CPD 0.3%–0.1 ...
Abbey L. Landini, Cyrus W. Abrahamson, Maya Frost, David Spielberg, Inbal Hazkani, Dana M. Thompson, Jonathan B. Ida, Sarah Maurrasse, Taher Valika   +8 more
wiley   +1 more source

MEK Inhibitor Associated Airway Injury in an Infant With Noonan Syndrome: A Case Report

The Laryngoscope, EarlyView.
An infant with Noonan syndrome treated with trametinib developed extensive mucosal sloughing of the upper and lower airway, followed by severe supraglottic scarring. Clinicians should consider airway toxicity as a potential adverse effect of MEK inhibitor therapy.
Veronica Drozdowski‐Nuccio, Rachel D. Yoon, Steven Tomasi, Dana M. Thompson, Inbal Hazkani   +4 more
wiley   +1 more source

Ostéogénèse imparfaite létale: diagnostic anténatal

The Pan African Medical Journal, 2016
L'ostéogenèse imparfaite (OI) est un groupe hétérogène de maladies affectant le collagène de type I et caractérisées par une fragilité osseuse. Les formes létales sont rares et se caractérisent par une micromélie avec déformation des membres.
Houda El Mhabrech, Ahmed Zrig, Ines Mazhoud, Leila Njim, Aouatef Hajjeji, Raja Faleh, Ch Hafsa   +6 more
doaj   +1 more source