Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Advanced Science, EarlyView.Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
Teacher Sorting, Teacher Quality, and Student Composition: Evidence from Norway [PDF]
Using panel data for Norwegian schools, we establish a two-equation supply and demand model for teachers with approved education. Taking into account nationally determined teacher pay and a strict teacher appointment rule, the data enable us to ...
Bjarne Strøm +2 more
core
Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis
Advanced Science, EarlyView.The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang +14 more
wiley +1 more source
Academic Competence, Teacher-Student Relationship, and Violence and Victimisation in Adolescents: The Classroom Climate as a Mediator. [PDF]
Int J Environ Res Public Health, 2021 Jiménez TI +5 more
europepmc +1 more source
Advanced Science, EarlyView.A pH/ROS‐dual‐responsive injectable hydrogel, formed by dynamic boronic ester and Schiff base crosslinking, co‐delivers enoblituzumab (B7‐H3 blocker) and Cl‐amidine (NETs suppressor). Via localized intratumoral delivery, it synergistically reprograms the immunosuppressive tumor microenvironment, overcomes T cell infiltration barriers, restores ...
Huan Li +12 more
wiley +1 more source
Advanced Science, EarlyView.A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du +17 more
wiley +1 more source
Teacher-Student Relationship Quality and Classroom Climate From the Student Perspective: Adaptation of the SPARTS-E in the Spanish Context7. [PDF]
Child Care Health DevGarcia-Rodriguez L +2 more
europepmc +1 more source
Lessons learnt from SACMEQII: South African student performance in regional context [PDF]
In regional context, South African students benefit from above average levels of public and private education resources. However, their performance on international tests – including SACMEQII (Southern African Consortium for Monitoring Educational ...
Megan Louw, Servaas van der Berg
core
Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids
Advanced Science, EarlyView.Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang +12 more
wiley +1 more source
The teacher-student relationship in inclusive contexts: the role of mentalization and closeness. [PDF]
Front PsycholCecere G +6 more
europepmc +1 more source