Results 91 to 100 of about 438,341 (309)
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
Advanced Science, EarlyView.The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
Preparing Tomorrow’s World Language Teacher Today: The Case for Seamless Induction [PDF]
, 2009 This essay is a call to action. It offers a comprehensive overview of the challenges facing world language (WL) teacher educators and their employers, the K-12 schools, during the teacher induction period.
Davis-Wiley, Patricia +2 more
core +1 more source
Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly
Advanced Science, EarlyView.Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao +5 more
wiley +1 more source
Sakarya University Journal of Education, 2016 Bu çalışmada öğretmen adaylarının eleştirel düşünme eğilimlerinin çevre etiği yaklaşımları üzerindeki etkisi araştırılmıştır. Araştırma modelini genel tarama modellerinden ilişkisel tarama modeli oluşturmaktadır.
Mehpare Saka
doaj +1 more source
Stars and saints: professional conversations for enhancing classroom practices [PDF]
, 2016 This paper explores a reflective activity - professional conversation. In so doing, it recalls the recent experience of working alongside 'starring' teachers who are dedicated to serving the poor in areas of deprivation.
Luby, Antony
core +3 more sources
Advanced Science, EarlyView.During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen +10 more
wiley +1 more source
Six Districts Begin the Principal Pipeline Initiative [PDF]
, 2013 This first report of an ongoing evaluation of The Wallace Foundation's Principal Pipeline Initiative describes the six participating school districts' plans and activities during the first year of their grants. The evaluation, conducted by Policy Studies
Brenda J. Turnbull +4 more
core
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, EarlyView.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis
Advanced Science, EarlyView.The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang +14 more
wiley +1 more source
“You Want Me To Do What?” The Benefits of Co-teaching in the Middle Level [PDF]
, 2017 Exemplary middle schools use interdisciplinary teaming which often involves some level of co-planning, co-teaching, and co-assessing. In addition to this collaborative foundation, federal mandates for supporting students have led to frequent co-teaching ...
Hurd, Ellis, Weilbacher, Gary
core +1 more source