Results 241 to 250 of about 1,043,550 (309)

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Variable co-adaptation: exploring the emergence of teacher-student interaction patterns in award-winning EFL classes through the CDST lens. [PDF]

Front Psychol
Chen B, Zhang W, Xie Y.
europepmc   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Research on the evolution of physical teachers and physical teaching policy: A perspective from China. [PDF]

PLoS One
Xiong M, Yan B, Xu R, Liu F, Dong C.
europepmc   +1 more source

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

Advanced Science, EarlyView.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu, Jiajia Zhuo, Xiaoquan Hong, Shihao Rao, Yafang Ye, Dandan Kang, Huifang Peng, Huiqin Zhuo   +7 more
wiley   +1 more source

Development and validation of a culturally adapted clinical teacher evaluation form in Thailand. [PDF]

Korean J Med Educ
Suebbook C, Teeracharoensub RS, Puranitee P, Sumrithe S, Supawattanabodee B, Thokanit NS, Pakakasama S.   +6 more
europepmc   +1 more source

Secondary School Student Perceptions of Beginning Teachers' Teaching Behaviours and Their Academic Engagement: Multilevel Modelling. [PDF]

Behav Sci (Basel)
Maulana R, Helms-Lorenz M, Suhre C.
europepmc   +1 more source

Coaching Teachers to Implement Equity and Social and Emotional Learning Focused Curricula in the Classroom: Insights from a Randomized Controlled Trial. [PDF]

J Educ Psychol Consult
Franco MP, Rouiller S, Bradshaw CP, Pas ET, Pandey T, Kaihoi CA, Bottiani JH.   +6 more
europepmc   +1 more source

Student satisfaction in transnational higher education in China: A mixed-methods study across Australian, German, and US cooperative programmes. [PDF]

PLoS One
Hu M.
europepmc   +1 more source

The impact of the mathematical adversity quotient on preparatory students' mathematics learning engagement: moderated mediation effect analysis. [PDF]

Front Psychol
Liu J, Sun Y, Li Y.
europepmc   +1 more source