Results 221 to 230 of about 5,710,845 (340)

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen   +12 more
wiley   +1 more source

Complete Issue Volume 3 Issue 1

open access: yesJournal of the Scholarship of Teaching and Learning, 2012
Editor, Journal of the Scholarship of Teaching and Learning
doaj  

PLXDC1+ Tumor‐Associated Pancreatic Stellate Cells Promote Desmoplastic and Immunosuppressive Niche in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du   +12 more
wiley   +1 more source

Complete Issue Volume 10 Issue 1

open access: yesJournal of the Scholarship of Teaching and Learning, 2012
Editor, Journal of the Scholarship of Teaching and Learning
doaj  

CTLT Newsletter: The Instructional and Pedagogical Resource Center for Pace Faculty [PDF]

open access: yes, 2011
Center for Teaching, Learning and Technology   +1 more
core   +1 more source

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