Results 61 to 70 of about 325,851 (265)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Academic Achievement and Attitude of Nursing Students in Three Different Approaches to Teaching English [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2017
Introduction: The need for English proficiency as an international language and the means to obtain new scientific information is highly felt. Undoubtedly, one of the most important factors affecting language learning is the teaching method.
Ayoub Garshasbi, Elham Khorsand, Ali Taghizadeh   +2 more
doaj  

Survey and analysis of effect of online teaching of "Military Epidemiology" course: based on the students' perspective [PDF]

Yixue xinzhi zazhi
Objective Taking the course "Military Epidemiology" as an example to evaluate the effect of online teaching, and explore suitable online teaching methods for military medical colleges based on the students' perspective.Methods We conducted an anonymous ...
WU Na, XIANG Ying, YUAN Zhiquan, XIA Tingting, HU Qin, CHEN Zheng, CAI Tongjian, ZHANG Yao, LI Yafei, WU Shuxing, MA Xiangyu   +10 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Internet-Based Educational Instrument and Methods in Medical Sciences Education [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2017
Introduction: Medical faculty members are often looking for new instruments in their teaching. Such instruments can be found in internet-based technologies.
Fariba Haghani, Habibolah Rezaei
doaj  

Difficulties in Applying a Student-Centered Approach in Modern Russian Higher Education

Высшее образование в России, 2020
The article attempts to define the application of student-centered approach in foreign language teaching at the Department of Foreign Languages in Engineering (Nosov Magnitogorsk State Technical University). The relevance of the research lies in the fact
O. V. Kisel, A. I. Dubskikh, A. V. Butova   +2 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source