Results 51 to 60 of about 325,851 (265)
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Journal of Curriculum Studies, 2007 本文主要在了解我國大學生的課業學習經驗，並比較一般生與技職生之間的差異。研究結果發現：一般大學教師的教學方式及課程評量與技職教師有部分差異，大學教師使用的教學法中，僅「單向講課教學」較技職教師多，「解題教學」則是技職教師採用較多；評量方面，一般教師使用紙筆測驗較多，而技職教師則在口試及實作評量方面使用較多；兩類學生對有助學習教學法的看法差別不大；教師採用的教學方式與學生認為有助其學習之教學法都屬低度相關，其中教師最常採用的單向講授法卻是學生認為與其學習相關最低的教學法 ...
劉鎔毓Jung-Yu Liu
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Implementation of Project Activities in the System of StudentCentered Learning
Высшее образование в России, 2022 The article addresses the educational project activities implementation at universities as part of the student-centered learning and a means to raise the effectiveness of students’ professional training.
I. N. Mishin
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
CONSTRUCTING THE SKETCH AND THE DRAWING AT A PROPER SCALE OF AN OBJECT
Journal of Industrial Design and Engineering Graphics, 2019 This paper presents a teaching activity having the topic „Constructing the sketch and the drawing at a proper scale of an object” and is addressed to the teachers who teach technical drawing in technical university education, but also to the students ...
Mihaela Rodica CLINCIU
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source