Results 91 to 100 of about 12,001,274 (358)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Fermatean Neutrosophic Fuzzy Methodology for Teaching Quality Analysis in University Basketball Training [PDF]

open access: yesNeutrosophic Sets and Systems
University basketball training plays a pivotal role in developing athletes' technical, tactical, and physical skills. Analysis of teaching quality in this context is essential for optimizing training methodologies, enhancing player performance, and ...
Yongzhi Wang, Ruifang Li, Mingtao Guo
doaj   +1 more source

Teacher Contract Non-Renewal in the Rocky Mountains [PDF]

open access: yes, 2018
Success for students in the 21st century increasingly relies on competencies and proficiencies typically available on]y through formal educational processes.
Dam, Margaret   +2 more
core   +1 more source

High-Quality Teaching

open access: yesThe Rural Educator, 2018
This article was adapted from a Policy Brief with the same title, published by the Appalachia Educational Laboratory. This work was sponsored wholly or in part by the Institute of Education Sciences (IES), U.S. Department of Education, under contract number ED-01-C0-0016. Its contents do not necessarily reflect the views of IES, the Department,
Aimee Howley, Craig B. Howley
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Urban heat island monitoring and intelligent prediction method based on big data analysis

open access: yesSustainable Energy Research
Frequent extreme heat events in urban areas have brought growing public attention to the urban heat island effect. However, traditional monitoring techniques are unable to handle high-dimensional data, which limits their application in real-world ...
Lin Wang
doaj   +1 more source

Teaching quality, social mobility and ‘opportunity’ in England: the case of the teaching and leadership innovation fund

open access: yes, 2021
Drawing on data from a study of the changing landscape for teachers’ professional development (PD) in England, this paper addresses the provision of PD for teachers in schools serving high-poverty communities designated as ‘Opportunity Areas’.
S. Steadman, V. Ellis
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Relevance of meeting general outpatients’ information needs to their perceptions of healthcare quality in a hospital in Ghana: a Healthcare Quality Survey using modified SERVQUAL analysis

open access: yesBMJ Open Quality
Background Patients determine quality of healthcare by their perception of the gap between the healthcare they experience/receive and that which they expect.
Adom Manu, Anita Ago Asare, Elom Otchi
doaj   +1 more source

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