Results 81 to 90 of about 2,260,845 (299)

A Novel Turbulence Trigger for Neoclassical Tearing Modes in Tokamaks

, 2003
"Stochastic trigger by microturbulence for neoclassical tearing mode (NTM) is studied. NTM induces topological change of magnetic structure and has subcritical nature.
"Itoh, S.-I., Itoh, K., Yagi, M."
core  

Kinetic simulations of the coupling between current instabilities and reconnection in thin current sheets [PDF]

Nonlinear Processes in Geophysics, 2000
We investigate the coupling between current and tearing instability modes of a thin current sheet using the particle code GISMO. We identify pure tearing modes (kx≠ 0), instabilities in the current flow direction (ky≠ 0) and general 3D reconnection modes
T. Wiegelmann, J. Büchner
doaj  

Dynamic mitigation of the tearing mode instability in a collisionless current sheet. [PDF]

Sci Rep, 2021
Gu YJ, Kawata S, Bulanov SV.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Impurity radiation seeding of neoclassical tearing mode growth

Nuclear Fusion
The physics of neoclassical tearing modes (NTMs) is of great concern to tokamak plasma stability and performance, especially in the burning plasma regime.
Shiyong Zeng, Ping Zhu, Eric C. Howell
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Plate Tearing Under Mixed Mode Loading [PDF]

, 2016
Cohesive-zone finite element modeling is often the technique of choice when dealing with extensive crack growth in large-scale ductile sheet metal structures.
Andersen, Rasmus Grau, Felter, Christian Lotz, Nielsen, Kim Lau   +2 more
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Physics-guided attention-aware convolutional neural networks for identification of magnetic islands in the tearing mode on EAST tokamak

Nuclear Fusion
The tearing mode (TM), a large-scale magnetohydrodynamic instability in tokamak, typically disrupts the equilibrium magnetic surfaces, leads to the formation of magnetic islands, reduces core electron temperature and density, thus resulting in ...
Feifei Long, Yian Zhao, Yunjiao Zhang, Chenguang Wan, Yinan Zhou, Ziwei Qiang, Kangning Yang, Jiuying Li, Tonghui Shi, Bihao Guo, Yang Zhang, Hailing Zhao, Ang Ti, Adi Liu, Chu Zhou, Jinlin Xie, Zixi Liu, Ge Zhuang, the EAST Team   +18 more
doaj   +1 more source

Nonlinear drift tearing modes [PDF]

, 1979
It is shown analytically and with a numerical code that the nonlinear growth and saturation of magnetic islands in tokamaks is not affected by diamagnetic corrections. Diamagnetic effects change the linear growth and introduce mode rotation, which persists in the nonlinear regime.
Monticello, D. A., White, R. B.
openaire   +2 more sources