Results 61 to 70 of about 313,339 (344)

Fast and Sensitive Quantification of AccQ-Tag Derivatized Amino Acids and Biogenic Amines by UHPLC-UV Analysis from Complex Biological Samples

Metabolites, 2022
Metabolomic analysis of different body fluids bears high importance in medical sciences. Our aim was to develop and validate a fast UHPLC-UV method for the analysis of 33 amino acids and biogenic amines from complex biological samples.
Andrea Guba, Orsolya Bába, József Tőzsér, Éva Csősz, Gergő Kalló   +4 more
doaj   +1 more source

Incidence of Second Anterior Cruciate Ligament Tears and Identification of Associated Risk Factors From 2001 to 2010 Using a Geographic Database

Orthopaedic Journal of Sports Medicine, 2017
Background: The reported rate of second anterior cruciate ligament (ACL) injuries (20%-30%), including graft failure and contralateral ACL tears, after ACL reconstruction (ACLR) or nonoperative therapy indicates that multiple factors may predispose ...
Nathan D. Schilaty, C. Nagelli, Nathaniel A Bates, Thomas L Sanders, A. Krych, M. Stuart, T. Hewett   +6 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Tear protein analysis in presumed congenital alacrima

Clinical Ophthalmology, 2018
Shigeharu Yaginuma,1 Yoko Akune,2 Chika Shigeyasu,1,2 Yoji Takano,3 Masakazu Yamada1 1Department of Ophthalmology, Kyorin University School of Medicine, Tokyo 181-8611, Japan; 2Division for Vision Research, National Institute of Sensory Organs, National
Yaginuma S, Akune Y, Shigeyasu C, Takano Y, Yamada M   +4 more
doaj  

A New Immortalized Human Lacrimal Gland Cell Line

Cells
The lacrimal gland is crucial for maintaining ocular health by producing the aqueous component of the tear film, which hydrates and nourishes the ocular surface.
Sophie Gleixner, Ingrid Zahn, Jana Dietrich, Swati Singh, Alice Drobny, Yanni Schneider, Raphael Schwendner, Eileen Socher, Nicolas Blavet, Lars Bräuer, Antoniu-Oreste Gostian, Matthias Balk, Gundula Schulze-Tanzil, Claudia Günther, Friedrich Paulsen, Philipp Arnold   +15 more
doaj   +1 more source

Tears for the Fallen [PDF]

The Permanente Journal, 2016
“Trauma 99 activation, ETA 5 min!” As an emergency medicine resident, this type of overhead page is what gets my adrenaline pumping. Finally, I thought, I’ve been waiting for some action all night. I looked over at the call sheet: 30-year-old male, single gunshot wound to the torso, CPR in progress.
openaire   +3 more sources

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Tear ascorbic acid levels and the total antioxidant status in contact lens wearers: A pilot study

Indian Journal of Ophthalmology, 2009
Aims: The tear ascorbate owing to its high concentration, functions as an effective antioxidant against the oxidative damage of cornea. Contact lens wearers (CLW) are prone to oxidative stress due to the lens-induced hypoxic conditions.
Venkata Sai, Narayanasamy Angayarkanni, Srinivasan Vidhya, Iyer Geetha, Sivaramakrishnan Ramakrishnan, Subramanian Madhumathi, Mahadevan Rajeshwari   +6 more
doaj  

A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases

Frontiers in Medicine
Electrochemical biosensors can provide an economical, accurate and rapid method for early screening of disease biomarkers in clinical medicine due to their high sensitivity, selectivity, portability, low cost and easy manufacturing, and multiplexing ...
Fushen Zhang, Weiye Xu, Zejun Deng, Jufang Huang   +3 more
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source