Results 1 to 10 of about 15,491 (154)

There is techne and phronesis in movement: A beautiful combination for health and well-being!

Turkish Journal of Kinesiology
Drawing on Aristotle’s concepts of techne (art or craft) and phronesis (practical wisdom), the purpose of this concept-based article was to showcase that there is techne and phronesis in movement, including their interrelations for the long-lasting love ...
Maria Kosma
exaly   +3 more sources

A SARS-CoV-2 antigen rapid diagnostic test for resource limited settings

Scientific Reports, 2021
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19 disease. RT-qPCR has been the primary method of diagnosis; however, the required infrastructure is lacking in many developing countries and the virus has ...
Erica Frew, Douglas Roberts, Shelly Barry, Matthew Holden, Amanda Restell Mand, Emily Mitsock, Enqing Tan, Wei Yu, Johan Skog   +8 more
doaj   +1 more source

Use of Lateral Flow Immunoassay to Characterize SARS-CoV-2 RBD-Specific Antibodies and Their Ability to React with the UK, SA and BR P.1 Variant RBDs

Diagnostics, 2021
Identifying anti-spike antibodies that exhibit strong neutralizing activity against current dominant circulating variants, and antibodies that are escaped by these variants, has important implications in the development of therapeutic and diagnostic ...
Enqing Tan, Erica Frew, Jeff Cooper, John Humphrey, Matthew Holden, Amanda Restell Mand, Jun Li, Shaya Anderson, Ming Bi, Julia Hatler, Anthony Person, Frank Mortari, Kevin Gould, Shelly Barry   +13 more
doaj   +1 more source

Exosome based analysis for Space Associated Neuro-Ocular Syndrome and health risks in space exploration

npj Microgravity, 2022
Molecular profiling to characterize the effects of environmental exposures is important from the human health and performance as well as the occupational medicine perspective in space exploration.
Sudipto K. Chakrabortty, Yevgenia L. Khodor, Robert R. Kitchen, Dulaney L. Miller, Kailey M. Babcock, Kyle S. Manning, Steven P. Lang, Vasisht Tadigotla, Wei Yu, Eric Bershad, Johan Skog, Susana Zanello   +11 more
doaj   +1 more source

A urine-based Exosomal gene expression test stratifies risk of high-grade prostate Cancer in men with prior negative prostate biopsy undergoing repeat biopsy

BMC Urology, 2020
Background Initial prostate biopsy often fails to identify prostate cancer resulting in patient anxiety, especially when clinical features such as prostate specific antigen (PSA) remain elevated, leading to the need for repeat biopsies.
James McKiernan, Mikkel Noerholm, Vasisht Tadigotla, Sonia Kumar, Phillipp Torkler, Grannum Sant, Jason Alter, Michael J. Donovan, Johan Skog   +8 more
doaj   +1 more source

Fluorescent glycan fingerprinting of SARS2 spike proteins

Scientific Reports, 2021
Glycosylation is the most common post-translational modification and has myriad of biological functions. However, glycan analysis has always been a challenge.
Zhengliang L. Wu, James M. Ertelt
doaj   +1 more source

Endoglycosidase assay using enzymatically synthesized fluorophore-labeled glycans as substrates to uncover enzyme substrate specificities

Communications Biology, 2022
Enzymatic synthesis of fluorophore-labeled glycans and their usage of substrates reveals substrate specificities of endoglycosidases.
Zhengliang L. Wu, James M. Ertelt
doaj   +1 more source

Establishment of a platform imaged capillary isoelectric focusing (icIEF) characterization method for adeno-associated virus (AAV) capsid proteins

Green Analytical Chemistry, 2022
Herein we describe a platform method to study the charge heterogeneity of adeno-associated virus (AAV) capsid proteins. The method, based on imaged capillary isoelectric focusing (icIEF) with native fluorescence imaging detection, was validated, and can ...
Jiaqi Wu, Chris Heger
doaj   +1 more source

The hidden foundation of polis in Hobbes's theory of liberalism [PDF]

Sociološki Pregled, 2021
In the article the author reflects upon the issue of the basis of Hobbes's theory of liberalism i.e. examines the way how a par excellence theory of Modernity shifts from being a political ontology into apolitical haunt logy proper.
Koljević-Grifit Bogdana N., Grifit Džejms E.K.   +1 more
doaj   +1 more source

Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma

Oncogenesis, 2021
CIC-DUX4 sarcoma (CDS) is a highly aggressive and metastatic small round type of predominantly pediatric sarcoma driven by a fusion oncoprotein comprising the transcriptional repressor Capicua (CIC) fused to the C-terminal transcriptional activation ...
Darko Bosnakovski, Elizabeth T. Ener, Mark S. Cooper, Micah D. Gearhart, Kevin A. Knights, Natalie C. Xu, Christian A. Palumbo, Erik A. Toso, Graham P. Marsh, Hannah J. Maple, Michael Kyba   +10 more
doaj   +1 more source