Results 21 to 30 of about 19,007 (252)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
CellsAn essential aspect of harnessing the potential of pluripotent stem cells (PSCs) and their derivatives for regenerative medicine is the development of animal-free and chemically defined conditions for ex vivo cultivation.
Xi Lu +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Dress or costume? The role of fashion in painting and life of Olga Boznańska [PDF]
, 2021 In Olga Boznańska’s portrait painting, clothes necessarily play an important role, and in her paintings one can trace changes in fashion, especially women’s fashion, over the course of fifty years.
Straszewska, Anna
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Techne and impossibility: re-reading Zizek's ideology-critique as geisteskritik [PDF]
, 2010 This discussion delineates and explores Zizek's ideology-critique towards the end of conceptually distinguishing the deployment of techne as the other side of impossibility, as revealed by his dialectical materialism.
Hourigan, Daniel
core
, 2022 The fictional short story “Torn” touches on the themes of “evil” in children being an outlet for their internal struggles and the ugly discovery of self-awareness.
Emond, Michelle
core
Between Art and Industry – Charles Frederick Worth's attitude towards the changes in Fashion in the second half of the 19th century [PDF]
, 2021 The article analyzes the attitude of Charles Frederick Worth (1825–1895) towards the changes that took place in women’s fashion from the mid-nineteenth century. The key point of his activity was to present himself as an artist.
Szaradowski, Piotr
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source