Results 21 to 30 of about 15,629 (230)
Advanced Science, EarlyView.Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong +12 more
wiley +1 more source
Advanced Science, EarlyView.Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu +9 more
wiley +1 more source
Problemos, 2008 Straipsnyje etimologiškai nagrinėjamos antikinės sąvokos bios, techne, logos. Kartu šios sąvokos interpretuojamos egzistencinės fenomenologijos kontekste.
Tomas Kačerauskas
doaj +1 more source
Matrix Stiffness Induces Endothelial Network Senescence
Advanced Science, EarlyView.Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song +6 more
wiley +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
Advanced Science, EarlyView.A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
La broma de Sócrates inspirado
Plato, 2021 El presente artículo defiende que Platón bromea cuando su Sócrates afirma estar inspirado o bajo posesión divina en Fedro 238d y Crátilo 396d. Para ello, primero se sitúan en contexto ambos pasajes; a continuación, se muestra que a lo largo de todo el ...
Jonathan Lavilla de Lera +1 more
doaj +1 more source
Advanced Science, EarlyView.The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source
Pedagogikkfagets kraft for lærerstudenter i profesjonsutdanningen
Nordisk tidsskrift for pedagogikk og kritikk, 2018 Det finnes lite forskningsbasert kunnskap om pedagogikkfagets betydning for lærerstudenters profesjonelle utvikling. Vi undersøkte pedagogikkfagets betydning for lærerstudenters profesjonelle utvikling ved å studere refleksjonstekster fra 62 studenter ...
Truls Nilsen Tangen +2 more
doaj +1 more source
Human Presencing in the Techne of a Contemplative Space
Dev Sanskriti: Interdisciplinary International Journal, 2020 In our colleges and universities, spaces are designated and set aside for specific uses. Students eat in dining halls, not in libraries; they sleep in dorm rooms, not in classrooms.
Mary Keator
doaj +1 more source
»Techne liebt Tyche und Tyche Techne«
, 2008 Die folgenden Überlegungen wollen die Frage künstlerischer Kreativität im Horizont des aristotelischen Denkens diskutieren. Künstlerische Kreativität ist in der Neuzeit in besonderer Weise zum Ausweis eines autonomen Subjektes geworden. Die Geschichte dieses Konzeptes hat dabei den Gegensatz von kreativer Autonomie und reproduktiv-imitativem ...
openaire +2 more sources