Results 131 to 140 of about 15,629 (230)
An animal component-free bioprocess for synthesizing 3D human matrix scaffolds using mesenchymal stromal cells. [PDF]
Stein SN, Braid LR.
europepmc +1 more source
ABSTRACT Background SSEA3, SSEA4, and Globo H glycosphingolipids have been implicated in tumor progression and immune modulation across various malignancies. However, their clinical significance in extrahepatic cholangiocarcinoma (eCCA) remains largely undefined.
Tsai‐Hsien Hung +6 more
wiley +1 more source
Gadamer, Habermas and Ricoeur: Toward a Hermeneutic Philosophy of Care. [PDF]
Ayres JRCM.
europepmc +1 more source
ABSTRACT The impact of Mycoplasma contaminations on in vitro test systems has been extensively discussed and in vitro studies have demonstrated various effects on the physiology of the contaminated cell line. Thus far, little is known about the effect of biologically active substances, such as viruses produced in contaminated cell lines on primary ...
Patricia Gogesch +5 more
wiley +1 more source
• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang +12 more
wiley +1 more source
A skeletal muscle atlas shows neuromuscular junction adaptations to growth and atrophy. [PDF]
Campanario S +26 more
europepmc +1 more source
ABSTRACT Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas and the most common cause of disease‐associated death for neurofibromatosis type 1 (NF1) patients. In the context of NF1, MPNSTs develop from benign premalignant precursors and the transition to malignancy is typically accompanied by loss of the polycomb ...
Madilyn R. Stahl +4 more
wiley +1 more source
Chondroid Soft Tissue Tumors With FOS::PABPN1 Fusion: A New Entity? About Two Cases
ABSTRACT Soft tissue tumors with chondroid matrix represent a heterogeneous group with persistent diagnostic challenges. Advances in molecular diagnostics have identified recurrent gene fusions in several chondroid neoplasms, predominantly involving FN1. Here, we report two cases of chondroid tumors harboring a novel FOS::PABPN1 fusion.
Jinane Kharmoum +7 more
wiley +1 more source
Development of autologous in vitro vascular models for use in preclinical biotherapeutic development. [PDF]
Lund E +7 more
europepmc +1 more source

