Regional expression of neurochemical metabolic pathways in the intestinal tract of the turkey (Meleagris gallopavo domesticus). [PDF]
Wickramasuriya SS +3 more
europepmc +1 more source
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke +24 more
wiley +1 more source
Methodological validation of Miro1 retention as a candidate Parkinson's disease biomarker. [PDF]
Drwesh L +12 more
europepmc +1 more source
ABSTRACT Background Decreased apical bicarbonate transport into the airway surface liquid (ASL) has been associated with decreased ASL pH, which can have adverse respiratory effects. However, the human CF epithelium can normalize ASL pH. Thus, we hypothesized that pH regulatory proteins other than the CFTR could be altered in the CF epithelium ...
Michael D. Davis +9 more
wiley +1 more source
Spectroscopic Studies of the Modulation of Metabolic Activity of HBE Cells by Doxorubicin Hydrochloride-Loaded SW480-Derived Exosomal Nanocarriers. [PDF]
Grel H +6 more
europepmc +1 more source
AP‐1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids
We show that in mouse intestinal organoids, AP‐1B is implicated in apical polarity, differentiation in the secretory lineage and proliferation. In particular, we propose that proliferation is controlled by AP‐1B via the mTOR and YAP pathways. Arrows show the functional links that were elucidated in this study, and dotted lines show putative downstream ...
Maela Duclos +5 more
wiley +1 more source
A skin colonizer disrupts inflammatory and humoral immune defenses in hidradenitis suppurativa. [PDF]
Agbogan VA +14 more
europepmc +1 more source
ABSTRACT Aim Glucagon is a key regulator of glucose and energy metabolism, yet the dose–response effects of glucagon on markers of metabolism in humans are not fully characterised. We investigated the dose‐dependent effects of glucagon on glucose metabolism, β‐cell secretion and markers of hepatic metabolism in healthy adults.
Sophie Betty Brock +4 more
wiley +1 more source
Inverse expression of Ten3 and Lphn2 across the developing mouse brain suggests a global strategy for circuit assembly. [PDF]
Chon U +5 more
europepmc +1 more source
An investigation of the sound of foam and its potential influence on the shampoo experience
This study investigates shampoo foam acoustics' impact on hair washing experience using binaural recordings and psychoacoustic analysis. Distinct foam sound profiles elicited varying emotional responses; early lathering induced negative emotions while later phases were positive.
Jia Wu +5 more
wiley +1 more source

