Results 171 to 180 of about 7,052,262 (327)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The Application of Biomechanics Combined with Human Body Structure in Volleyball Technical Analysis.
Comput Intell Neurosci, 2022 Jiang W, Zhao K.
europepmc +1 more source
Application status and technical analysis of chitosan-based medical dressings: a review. [PDF]
RSC Adv, 2020 Zhang S +6 more
europepmc +1 more source
Technical and Economic Analysis of the Use of Heat Pumps in a Public Facility [PDF]
, 2022 Radosław Wiekiera
openalex +1 more source
Foundations of Technical Analysis: Computational Algorithms, Statistical Inference, and Empirical Implementation [PDF]
Technical analysis, also known as "charting", has been a part of financial practice for many decades, yet little academic research has been devoted to a systematic evaluation of this discipline.
Andrew Lo, Harry Mamaysky, Jiang Wang
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
High beta and second stability region transport and stability analysis. Technical progress report
, 1994 M.H. Hughes, Michael Phillips
openalex +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Durability of smartphones: A technical analysis of reliability and repairability aspects.
J Clean Prod, 2021 Cordella M +3 more
europepmc +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source