Results 31 to 40 of about 1,228,905 (285)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
TECHNICAL DRAWING SKILL IMPROVEMENT WITH MEDIA PEMBELAJARAN MODUL GAMBAR TEKNIK FOR TECHNICAL DRAWING COURSE IN ENGINEERING DEPARTEMENT OF AUDIO VIDEO SMK NEGERI 2 YOGYAKARTA [PDF]
The purpose of this research is to find out the design of Modul Gambar Teknik, describing the learning process of technical drawing through Media Pembelajaran Modul Gambar Teknik in exertion to improve the technical drawing skill. In addition the purpose
Saputra, Aria Kaswara
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
RELEVANSI MATERI PEMBELAJARAN MENGGAMBAR TEKNIK SISWA KELAS XII SMK ST. MIKAEL SURAKARTA TERHADAP KEBUTUHAN DI INDUSTRI [PDF]
The research’s purpose aim are to: (1)knowing the relevance of technical drawing learning materials in SMK St.Mikael Surakarta far has been to support student mastery of the technical drawing materials industrial needs, (2)knowing the relevance of ...
Saputro, Herman +2 more
core
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
CONTRIBUTIONS FOR DEVELOPING OF A COMPUTER AIDED LEARNING ENVIRONMENT OF DESCRIPTIVE GEOMETRY
The paper presents the authors’ contributions for developing a computer code for teaching of descriptive geometry using the computer aided learning techniques.
Antonescu Ion +2 more
doaj
The technical drawing learning outcomes of students of SMK Piri 1 Yogyakarta tend to decline. This happened because the online learning process was not optimal during the COVID-19 epidemic.
Nurcholish Arifin Handoyono
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Meaning in the margins: postcolonial feminist methodologies in practical theology [PDF]
This paper troubles research approaches in practical theology by exploring how attention to lived experiences of marginalization in postcolonial feminist theologies shapes theological methodologies.
Radford, Clare Louise
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source

