Results 51 to 60 of about 3,409,340 (272)

THE STRUCTURE OF THE FORMS: A LEARNING THROUGH THE GRAPHIC IMAGE

open access: yesDaya, 2018
In the programming of the subject Graphic Representation, better known as Technical Drawing, in the lapum of Design careers at the University of Azuay, the experiences of the implementation of cognitive skills in the courses of the beginning of the ...
Álvaro Larriva Rivera
doaj   +1 more source

A Design-based Approach to Enhancing Technical Drawing Skills in Design and Engineering Education using VR and AR Tools

open access: yesVISIGRAPP, 2019
There are concerns from higher education (HE) institutions and industry about the decline in standards of technical drawings (TDs) due to the lack of understanding of basic geometric construction and the conventions of drafting skills that underpin the ...
Omar Huerta   +6 more
semanticscholar   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

APPLICATIONS USED IN TEACHING TECHNICAL DRAWING FOR DEVELOPING THE SPATIAL ABILITY OF THE STUDENTS

open access: yesJournal of Industrial Design and Engineering Graphics, 2022
The paper presents applications developed for teaching technical drawing. The purpose of the applications presented is to develop and improve the spatial ability of the students and their spatial perception of the objects. These applications are focused
Ramona CLINCIU, Rodica CLINCIU
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

‘ The Theoretical Eye’ translated by Anthony Auerbach [PDF]

open access: yesJournal of Art Historiography, 2011
In his article ‘L’œil théoricien’ (1988), written for the catalogue of an exhibition of works by Josef Albers (1888–1976), Hubert Damisch brought the complex of ideas elaborated in his major work on Renaissance painting to bear on the twentieth century ...
Hubert Damisch
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

An Approach to Improve Technical Drawing using VR and AR Tools

open access: yesComputer-Aided Design and Applications, 2019
. In this paper, the authors present the development of 3D interactive AR/VR teaching system from a design-based method to help engineering and product design students improve on critical and complex topics related to TD skills according to an ...
Omar Huerta   +4 more
semanticscholar   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

THE IMPORTANCE OF STUDY GEOMETRY DESCRIPTIVE METHODS IN LEARNING GRAPHICS DISCIPLINES

open access: yesJournal of Industrial Design and Engineering Graphics, 2021
The aim of this paper is to study the influence of auxiliary view method, as a method of descriptive geometry, in studying and recognizing the geometry of an object.
Manuela Nechita
doaj  

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