Results 41 to 50 of about 3,409,340 (272)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Mapping of Vocational School with Building Technical Drawing Concentration: Opportunities and Challenges in Construction Industry’s Needs

open access: yesProceedings of the 5th UPI International Conference on Technical and Vocational Education and Training (ICTVET 2018), 2019
In the last five years, the vocational secondary school (SMK) graduates absorption in the industry has been steadily declining. One still remains issues is the incompatibility of graduate competence with the skills required by the industry.
T. Megayanti   +2 more
semanticscholar   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

CONTRIBUTIONS FOR DEVELOPING OF A COMPUTER AIDED LEARNING ENVIRONMENT OF DESCRIPTIVE GEOMETRY

open access: yesJournal of Industrial Design and Engineering Graphics, 2009
The paper presents the authors’ contributions for developing a computer code for teaching of descriptive geometry using the computer aided learning techniques.
Antonescu Ion   +2 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Enhancing Effectiveness in Teaching and Learning Technical Drawing for Sustainable Development in Nigerian Technical Colleges

open access: yesInnovation of Vocational Technology Education, 2019
This study determined enhancing effectiveness in teaching and learning technical drawing for sustainable development in Nigerian technical colleges.
J. O. Oke, O. O. Olakotan
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

ON TEACHING DESCRIPTIVE GEOMETRY AT THE FACULTY OF CIVIL ENGINEERING OF IASI

open access: yesJournal of Industrial Design and Engineering Graphics, 2007
The main goal of this paper deals with specific didactic and methodical principles in the teaching of descriptive geometry elaborated and applied at the Faculty of Construction, “Gheorghe Asachi” Technical University of Iasi, Romania, for the students in
HÎNCU Graţiela, STĂNILĂ Aneta
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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