Results 41 to 50 of about 154,790 (287)

‘ The Theoretical Eye’ translated by Anthony Auerbach [PDF]

Journal of Art Historiography, 2011
In his article ‘L’œil théoricien’ (1988), written for the catalogue of an exhibition of works by Josef Albers (1888–1976), Hubert Damisch brought the complex of ideas elaborated in his major work on Renaissance painting to bear on the twentieth century ...
Hubert Damisch
doaj  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Design gallery browsers based on 2D and 3D graph drawing [PDF]

, 1997
Many problems in computer-aided design and graphics involve the process of setting and adjusting input parameters to obtain desirable output values. Exploring different parameter settings can be a difficult and tedious task in most such systems.
Andalman, Brad, Ruml, Wheeler, K. Ryall, J. Marks, B. Andalman, Shieber, Stuart, Marks, Joe, Ryall, Kathy, W. Ruml, S. Shieber   +9 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

THE STRUCTURE OF THE FORMS: A LEARNING THROUGH THE GRAPHIC IMAGE

Daya, 2018
In the programming of the subject Graphic Representation, better known as Technical Drawing, in the lapum of Design careers at the University of Azuay, the experiences of the implementation of cognitive skills in the courses of the beginning of the ...
Álvaro Larriva Rivera
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

CONSTRUCTING THE SKETCH AND THE DRAWING AT A PROPER SCALE OF AN OBJECT

Journal of Industrial Design and Engineering Graphics, 2019
This paper presents a teaching activity having the topic „Constructing the sketch and the drawing at a proper scale of an object” and is addressed to the teachers who teach technical drawing in technical university education, but also to the students ...
Mihaela Rodica Clinciu
doaj   +4 more sources

Collection of Technical Drawing Tasks for Non-Engineering Fields [PDF]

, 2023
Tato bakalářská práce se zabývá sestavením sbírky úloh pro technické kreslení pro nestrojírenské obory technických škol. V teoretické části se zabývá teorií, která je potřebná pro tvorbu úloh a další didaktickou teorií.
Tomáš Petrík
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source