Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Olga Bjelotomić, PhD in Technical Sciences
Olga Bjelotomić defended her PhD thesis High Resolution Geoid Modelling of Croatia at the Faculty of Geodesy, University of Zagreb on May 15, 2015. The Defense Committee consisted of Assoc. Prof.
Tomislav Bašić
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Difficulties and Trade-offs in Performance Evaluation in Social Sciences: A Turkish Perspective [PDF]
The main objective of this study is to briefly examine the process of performance evaluation in social sciences in Turkey from an international perspective and pinpoint the main difficulties and trade-offs involved in this process and suggest new ways of
Fikret Senses
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Ivan Racetin, PhD in Technical Sciences
On 19 June 2020, Ivan Racetin defended his doctoral thesis Anomaly detection on hyperspectral and multispectral digital images of a mine suspected area at the Faculty of Geodesy, University of Zagreb.
Racetin Ivan, Krtalić Andrija
doaj
THE PLACE AND SIGNIFICANCE OF PROBLEM SOLVING IN TEACHING GENERAL TECHNICAL SCIENCES
Xaydarqulov Otabek
openalex +1 more source
Technical issues in the conduct of large space platform experiments in plasma physics and geoplasma sciences [PDF]
Large, permanently-manned space platforms can provide exciting opportunities for discoveries in basic plasma and geoplasma sciences. The potential for these discoveries will depend very critically on the properties of the platform, its subsystems, and ...
Szuszczewicz, Edward P.
core +1 more source
The Impacts of Career-Technical Education on High School Completion and Labor Market Success [PDF]
[Excerpt] High school career-technical education (CTE) is a massive enterprise. Last year high school students spent more than 1.5 billion hours in vocational courses of one kind or another.
Bishop, John H., Mane, Ferran
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

