Results 71 to 80 of about 9,259 (217)

Explainable deep learning self‐supervised vision transformer for fundus‐based myopia classification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To develop and validate a self‐supervised vision transformer (ViT) for automated three‐class classification of Normal, High Myopia (HM), and Pathologic Myopia (PM) from colour fundus photographs, with anatomically faithful interpretability. Methods A DINOv2 self‐supervised ViT was fine‐tuned using a two‐stage transfer‐learning protocol
Eirini Maliagkani, Christos Tsoutsas, Nikolaos Papageorgiou, Ioannis D. Apostolopoulos, Nikolaos Papandrianos, Ilias Georgalas, Elpiniki Papageorgiou   +6 more
wiley   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

British Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig, Yusuf C. Erdoğan, Benjamin Gottschalk, Michael Gruber, Andrea Groselj‐Strele, Sandra Burgstaller, Wolfgang F. Graier, Roland Malli   +7 more
wiley   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Democratising Multi‐Projector Displays

Computer Graphics Forum, EarlyView.
Spatially augmented reality (SAR) transforms large, surround, collaborative experiences out of VR/AR headsets to the real world by merging content from projectors with the physical environment. This detailed state‐of‐the‐art survey reports on the advancements in multi‐projector aggregation and hardware technologies used to achieve SAR and build ...
Aditi Majumder, Muhammad Twaha Ibrahim
wiley   +1 more source

3D Character Reconstruction from Hand‐drawn Model Sheets

Computer Graphics Forum, EarlyView.
Abstract Hand‐drawn model sheets are widely used in character design to define 3D shape and appearance through sparse multi‐view drawings. Reconstructing 3D characters from such sparse inputs has traditionally been challenging due to insufficient visual information.
Hyejeong Yoon, Wonjong Jang, Yoonha Hwang, Seungyong Lee   +3 more
wiley   +1 more source

TreeON: Reconstructing 3D Tree Point Clouds from Orthophotos and Heightmaps

Computer Graphics Forum, EarlyView.
Abstract We present TreeON, a novel neural‐based framework for reconstructing detailed 3D tree point clouds from sparse top‐down geodata, using only a single orthophoto and its corresponding Digital Surface Model (DSM). Our method introduces a new training supervision strategy that combines both geometric supervision and a differentiable shadow and ...
Angeliki Grammatikaki, Johannes Eschner, Pedro Hermosilla, Oscar Argudo, Manuela Waldner   +4 more
wiley   +1 more source

Tangent Blow‐Ups for Processing Non‐Manifold Geometry

Computer Graphics Forum, EarlyView.
Abstract Many geometry processing pipelines implicitly assume their input data is a manifold, or is sampled from one, with a unique tangent plane at every point. Geometric data, however, routinely contains sharp features like edges, corners, self‐intersections, branching junctions, and other singularities, rendering standard methods ill‐defined at ...
Alice Petrov, Mohammad Sina Nabizadeh, Ana Dodik, Justin Solomon   +3 more
wiley   +1 more source

Advances in 4D Representation: Geometry, Motion, and Interaction

Computer Graphics Forum, EarlyView.
We survey 4D representation through three key pillars — geometry, motion, and interaction — offering a selective, representation‐centric perspective to guide researchers in choosing and customizing the right 4D representation for their tasks. Abstract We present a survey on 4D generation and reconstruction, a fast‐evolving subfield of computer graphics
M. Zhao, S. Nag, K. Wang, A. Vora, G. Ji, P. Chun, A. Mahdavi‐Amiri, H. Zhang   +7 more
wiley   +1 more source

Recent Trends in Inverse Rendering

Computer Graphics Forum, EarlyView.
This survey reviews 84 papers published between 2020 and 2025 on inverse rendering methods, introducing a taxonomy based on input data, scene representations, optimization strategies, and evaluation methods. We analyze emerging trends in neural, differentiable, and Gaussian‐splatting approaches, discuss applications, and identify key challenges and ...
S. Ullah, F. Pellacini, A. Giachetti
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source