Results 41 to 50 of about 33,299 (199)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Compendious review on 3D-printed gels for effluent treatment

Hybrid Advances
Direct ink writing (DIW) has emerged as an innovative and efficient method for gel synthesis, presenting numerous advantages over conventional techniques.
Apsara Panchapakesan, Priyanka Anil Dalave, Balasubramanian Kandasubramanian, Sikiru O. Ismail   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Scientific Opinion on the safety and efficacy of Pediococcus pentosaceus (DSM 14021, DSM 23688 and DSM 23689) as silage additives for all animal species [PDF]

EFSA Journal, 2013
Three strains of Pediococcus pentosaceus are each intended to improve the ensiling process at a dose of 1x108 CFU/kg fresh matter. This speciesis considered by EFSA to be suitable for the qualified presumption of safety approach to safety assessment.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Viscoelastic and Thermal Characterization of a Composite Material Based on Unsaturated Polyester Resin Reinforced with Perlite

Selected Scientific Papers: Journal of Civil Engineering
In this work, it was proposed to replace the conventional reinforcement of the unsaturated polyester resin by a mineral, from a siliceous volcanic rock of volcanic nature, perlite.
Dehas Ouided, Biskri Yasmina, Benzerara Mohammed, Babouri Laidi, Cherifi Acheref   +4 more
doaj   +1 more source

Efficacy of Friedland clay (montmorillonite–illite mixed layer clay) when used as a technological additive for all animal species

EFSA Journal, 2015
Friedland clay (montmorillonite–illite mixed layer clay mineral) was shown to be effective as a binder (at concentrations between 1 and 2 % in four different types of feed) and as an anticaking agent (at concentrations of 2 % in rolled oats, in a mixture
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Assessment of the efficacy of two feed additives consisting of Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) strains ATCC 55058 and ATCC 55942 for all animal species (FEFANA asbl)

EFSA Journal, 2022
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of two technological additives to improve ensiling of forages consisting of Lactiplantibacillus plantarum (formerly Lactobacillus plantarum ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Fašmon Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Noël Dierick, Montserrat Anguita, Rosella Brozzi, Jaume Galobart, Jordi Ortuño, Joana Revez   +23 more
doaj   +1 more source