Results 81 to 90 of about 182,310 (338)

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Scientific Opinion on the safety and efficacy of sodium benzoate as a silage additive for pigs, poultry, bovines, ovines, goats, rabbits and horses [PDF]

EFSA Journal, 2012
<p>Sodium benzoate is intended for use as a technological additive to improve the ensiling process at a proposed dose of 2 400 mg/kg fresh matter, the eventual use of the silage being for pigs, poultry, bovines, ovines, goats, rabbits and horses ...
EFSA Panel on Additives and Products or Substances used in Animal Feed
doaj   +1 more source

Additive noise effects in active nonlinear spatially extended systems

, 2012
We examine the effects of pure additive noise on spatially extended systems with quadratic nonlinearities. We develop a general multiscale theory for such systems and apply it to the Kuramoto-Sivashinsky equation as a case study.
D. TSELUIKO, D.T. PAPAGEORGIOU, G.A. PAVLIOTIS, Heagy, Horsthemke, Hyman, Hyman, Jolly, Lauritsen, López, M. PRADAS, Mecke, Obeid, Papageorgiou, Pavliotis, Pradas, S. KALLIADASIS, Sivashinsky, Tseluiko, Zaikin   +19 more
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Viscoelastic and Thermal Characterization of a Composite Material Based on Unsaturated Polyester Resin Reinforced with Perlite

Selected Scientific Papers: Journal of Civil Engineering
In this work, it was proposed to replace the conventional reinforcement of the unsaturated polyester resin by a mineral, from a siliceous volcanic rock of volcanic nature, perlite.
Dehas Ouided, Biskri Yasmina, Benzerara Mohammed, Babouri Laidi, Cherifi Acheref   +4 more
doaj   +1 more source

Scientific Opinion on the safety and efficacy of sodium bisulphate (SBS) for all animal species as preservative and silage additive, for pets and other non food‐producing animals (non‐food fur animals) as acidity regulator and for pets as flavouring

EFSA Journal, 2011
The additive (SBS) consists of sodium bisulphate without carrier materials. The applicants are seeking authorisation for SBS as a silage additive and for use as feed preservative for all animal species, as acidity regulator for pets and other non food ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Additive Manufacturing Applications in Biosensors Technologies

Biosensors
Three-dimensional (3D) printing technology, also known as additive manufacturing (AM), has emerged as an attractive state-of-the-art tool for precisely fabricating functional materials with complex geometries, championing several advancements in tissue engineering, regenerative medicine, and therapeutics.
Abraham Abbey Paul, Adedamola D. Aladese, And Robert S. Marks   +2 more
openaire   +3 more sources

Surface technology for additive manufacturing [PDF]

Plasma Processes and Polymers, 2019
AbstractAdditive manufacturing (AM) technologies are recognized as promising new approaches for the production of industrial goods. One of the major drawbacks, however, is the surface quality of parts prepared by AM. In the present paper, the potential of applying classical surface technology to efficiently improve the surface properties of AM products
Andreas Holländer, Patrick Cosemans
openaire   +2 more sources

A comparison of processing techniques for producing prototype injection moulding inserts. [PDF]

, 2019
This project involves the investigation of processing techniques for producing low-cost moulding inserts used in the particulate injection moulding (PIM) process.
Ewart, Paul
core  

The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]

, 2019
Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir, Emamian, Sattar S., Fotovvati, Behzad, Gisario, Annamaria, Mehrpouya, Mehrsha, Vosooghnia, Alireza   +5 more
core   +1 more source