Results 111 to 120 of about 103,802 (310)

Safety and efficacy of sorbitan monolaurate as a feed additive for all animal species

EFSA Journal, 2019
The additive sorbitan monolaurate consists of sorbitol (and its anhydrides) esterified with fatty acids derived from coconut oil. It is intended to be used as a technological additive, functional group: emulsifier, in feedingstuffs for all animal species,
EFSA Panel on Additives and Products or Substances used in Animal Feed (EFSA FEEDAP Panel), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Maryline Kouba, Mojca Kos Durjava, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Gabriele Aquilina, Georges Bories, Andrew Chesson, Carlo Nebbia, Derek Renshaw, Matteo Lorenzo Innocenti, Jürgen Gropp   +24 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

REPAIR MATERIAL MODIFICATION BY POLYMEROUS ADDITIVES WHILE TRANSPORT REPAIRING OF BUILDINGS AND ENGINEERING STRUCTURES

Nauka ta progres transportu, 2010
In the article one of directions of creation of a repair material with the set technological and operational properties by means of modifying additives of the directed or multifunctional action is considered.
A. N. Pshinjko, A. V. Krasniuk, B. G. Klochko, O. V. Ghromova, V. V. Palij   +4 more
doaj  

Assessment of the feed additive consisting of Lactiplantibacillus plantarum DSM 18113 for all animal species for the renewal of its authorisation (Pioneer Hi‐Bred International, Inc.)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) DSM 18113 as a technological additive ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Montserrat Anguita, Nicole Bozzi Cionci, Rosella Brozzi, Jaume Galobart, Yolanda García‐Cazorla, Matteo L. Innocenti, Joana Revez   +23 more
doaj   +1 more source

Вплив органічних та неорганічних поризаторів на властивості пористо-пустотілої будівельної кераміки [PDF]

, 2012
Здійснено технологічну оцінку органічних і неорганічних поризуючих добавок, що можуть використовуватися у виробництві пористо-пустотілої кераміки. Досліджено фізичні і технологічні властивості поризаторів.
Галушка, Ярослав Олегович, Міхеєнко, Лариса Олександрівна, Пилипчатін, О. В., Щукіна, Людмила Павлівна   +3 more
core  

Technological Advancements in Metal Additive Manufacturing Process – A Review

, 2021
Karthik Anand B., Sudhansu Ranjan Das, Ajit Kumar Khatua, Ch. Ramakrishna   +3 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Assessment of the feed additive consisting of Lactiplantibacillus plantarum ATCC 55943 for all animal species for the renewal of its authorisation (Pioneer Hi‐Bred International, Inc.)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) ATCC 55943 as a technological additive ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Montserrat Anguita, Nicole Bozzi Cionci, Rosella Brozzi, Jaume Galobart, Yolanda García‐Cazorla, Matteo L. Innocenti, Joana Revez   +24 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source