Results 111 to 120 of about 27,617 (304)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

REPAIR MATERIAL MODIFICATION BY POLYMEROUS ADDITIVES WHILE TRANSPORT REPAIRING OF BUILDINGS AND ENGINEERING STRUCTURES

Nauka ta progres transportu, 2010
In the article one of directions of creation of a repair material with the set technological and operational properties by means of modifying additives of the directed or multifunctional action is considered.
A. N. Pshinjko, A. V. Krasniuk, B. G. Klochko, O. V. Ghromova, V. V. Palij   +4 more
doaj  

Leaching Properties of Secondary Lead Slag Stabilized/Solidified with Cement and Selected Additives

, 2013
Sodium lead slag, generated during secondary lead production, is characterized as hazardous waste. The aim of the study was to investigate leaching mechanism and behaviour of lead and arsenic from sodium lead slag previously stabilized/solidified in ...
Korać, M., Kamberović, Željko, Štulović, M., Korać, Marija, Ivšić-Bajčeta, D., Ivsic-Bajceta, Dragana, Ristić, M., Anđić, Z., Anđić, Zoran, Štulović, Marija, Kamberović, Ž., Ristić, Mirjana   +11 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Assessment of the feed additive consisting of Pediococcus acidilactici NCIMB 30005 for all animal species for the renewal of its authorisation (Microferm ltd.)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of the authorisation of a preparation of Pediococcus acidilactici NCIMB 30005 as technological additive to ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Montserrat Anguita, Nicole Bozzi Cionci, Jaume Galobart, Matteo L. Innocenti, Joana Revez   +21 more
doaj   +1 more source

Additive Manufacturing Applications in Biosensors Technologies

Biosensors
Three-dimensional (3D) printing technology, also known as additive manufacturing (AM), has emerged as an attractive state-of-the-art tool for precisely fabricating functional materials with complex geometries, championing several advancements in tissue engineering, regenerative medicine, and therapeutics.
Abraham Abbey Paul, Adedamola D. Aladese, And Robert S. Marks   +2 more
openaire   +3 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Assessment of the feed additive consisting of Lactiplantibacillus plantarum DSM 18112 for all animal species for the renewal of its authorisation (Pioneer Hi‐Bred International, Inc.)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) DSM 18112 as a technological additive ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Montserrat Anguita, Nicole Bozzi Cionci, Rosella Brozzi, Joana Firmino, Jaume Galobart, Yolanda García‐Cazorla, Matteo L. Innocenti, Joana Revez   +26 more
doaj   +1 more source

Additives in food and their properties

, 2013
The aim of this work is to deepen the knowledge about additives in foods, the importance of technological additives in foods, their properties and effects on human health.
TYLOVÁ, Kristýna
core