Results 101 to 110 of about 114,747 (258)
Characterization and Technology of Nanomaterials [PDF]
openaire +1 more source
Technology recognition and traffic characterization for wireless technologies in ITS band
Girmay, Merkebu +5 more
openaire +2 more sources
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The electrochemical reduction of CO2 (eCO2R) from carbon capture solutions, such as (bi)carbonate, offers a promising pathway for energy-efficient carbon recycling compared to traditional gas-phase approaches.
Ramato Ashu Tufa +8 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Progress and outlook of experimental techniques in lacustrine shale reservoir characterization
Shale reservoirs, as a significant category of unconventional oil and gas resources, possess substantial potential. Compared to marine shale reservoirs, lacustrine shale reservoirs are characterized by pronounced heterogeneity, complex pore structures ...
Yangyu Zhang, Tengjia Li
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Mechanically Coupled MEMS Tandem Micromirrors for Bidirectional Electrostatic Actuation
The concept, design, technological fabrication and experimental characterization of a function unit consisting of two mechanically coupled MEMS micromirrors, denoted in this paper as Tandem Micromirrors (TMM) unit, are presented.
Sally Abuhasnah +5 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

